Gene name: ATG13

Uniprot entry:

O75143

Protein names:

Autophagy-related protein 13

Protein sequence:

1_METDL 6_ NSQDR 11_ KDLDK 16_ FIKFF 21_ ALKTV 26_ QVIVQ 31_ ARLGE 36_ KICTR 41_ SSSSP 46_ TGSDW 51_ FNLAI 56_ KDIPE 61_ VTHEA 66_ KKALA 71_ GQLPA 76_ VGRSM 81_ CVEIS 86_ LKTSE 91_ GDSME 96_ LEIWC 101_ LEMNE 106_ KCDKE 111_ IKVSY 116_ TVYNR 121_ LSLLL 126_ KSLLA 131_ ITRVT 136_ PAYRL 141_ SRKQG 146_ HEYVI 151_ LYRIY 156_ FGEVQ 161_ LSGLG 166_ EGFQT 171_ VRVGT 176_ VGTPV 181_ GTITL 186_ SCAYR 191_ INLAF 196_ MSTRQ 201_ FERTP 206_ PIMGI 211_ IIDHF 216_ VDRPY 221_ PSSSP 226_ MHPCN 231_ YRTAG 236_ EDTGV 241_ IYPSV 246_ EDSQE 251_ VCTTS 256_ FSTSP 261_ PSQLS 266_ SSRLS 271_ YQPAA 276_ LGVGS 281_ ADLAY 286_ PVVFA 291_ AGLNA 296_ THPHQ 301_ LMVPG 306_ KEGGV 311_ PLAPN 316_ QPVHG 321_ TQADQ 326_ ERLAT 331_ CTPSD 336_ RTHCA 341_ ATPSS 346_ SEDTE 351_ TVSNS 356_ SEGRA 361_ SPHDV 366_ LETIF 371_ VRKVG 376_ AFVNK 381_ PINQV 386_ TLTSL 391_ DIPFA 396_ MFAPK 401_ NLELE 406_ DTDPM 411_ VNPPD 416_ SPETE 421_ SPLQG 426_ SLHSD 431_ GSSGG 436_ SSGNT 441_ HDDFV 446_ MIDFK 451_ PAFSK 456_ DDILP 461_ MDLGT 466_ FYREF 471_ QNPPQ 476_ LSSLS 481_ IDIGA 486_ QSMAE 491_ DLDSL 496_ PEKLA 501_ VHEKN 506_ VREFD 511_AFVET

Protein annotations

Protein functions:

1: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation