Gamma-glutamylcyclotransferase (EC 4.3.2.9) (Cytochrome c-releasing factor 21)
1_MANSG 6_ CKDVT 11_ GPDEE 16_ SFLYF 21_ AYGSN 26_ LLTER 31_ IHLRN 36_ PSAAF 41_ FCVAR 46_ LQDFK 51_ LDFGN 56_ SQGKT 61_ SQTWH 66_ GGIAT 71_ IFQSP 76_ GDEVW 81_ GVVWK 86_ MNKSN 91_ LNSLD 96_ EQEGV 101_ KSGMY 106_ VVIEV 111_ KVATQ 116_ EGKEI 121_ TCRSY 126_ LMTNY 131_ ESAPP 136_ SPQYK 141_ KIICM 146_ GAKEN 151_ GLPLE 156_ YQEKL 161_ KAIEP 166_ NDYTG 171_ KVSEE 176_ IEDII 181_KKGET
1: Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis (PubMed:18515354). Induces release of cytochrome c from mitochondria with resultant induction of apoptosis (PubMed:16765912)