Zinc finger protein ZPR1 (Zinc finger protein 259)
1_MAASG 6_ AVEPG 11_ PPGAA 16_ VAPSP 21_ APAPP 26_ PAPDH 31_ LFRPI 36_ SAEDE 41_ EQQPT 46_ EIESL 51_ CMNCY 56_ CNGMT 61_ RLLLT 66_ KIPFF 71_ REIIV 76_ SSFSC 81_ EHCGW 86_ NNTEI 91_ QSAGR 96_ IQDQG 101_ VRYTL 106_ SVRAL 111_ EDMNR 116_ EVVKT 121_ DSAAT 126_ RIPEL 131_ DFEIP 136_ AFSQK 141_ GALTT 146_ VEGLI 151_ TRAIS 156_ GLEQD 161_ QPARR 166_ ANKDA 171_ TAERI 176_ DEFIV 181_ KLKEL 186_ KQVAS 191_ PFTLI 196_ IDDPS 201_ GNSFV 206_ ENPHA 211_ PQKDD 216_ ALVIT 221_ HYNRT 226_ RQQEE 231_ MLGLQ 236_ EEAPA 241_ EKPEE 246_ EDLRN 251_ EVLQF 256_ STNCP 261_ ECNAP 266_ AQTNM 271_ KLVQI 276_ PHFKE 281_ VIIMA 286_ TNCEN 291_ CGHRT 296_ NEVKS 301_ GGAVE 306_ PLGTR 311_ ITLHI 316_ TDASD 321_ MTRDL 326_ LKSET 331_ CSVEI 336_ PELEF 341_ ELGMA 346_ VLGGK 351_ FTTLE 356_ GLLKD 361_ IRELV 366_ TKNPF 371_ TLGDS 376_ SNPGQ 381_ TERLQ 386_ EFSQK 391_ MDQII 396_ EGNMK 401_ AHFIM 406_ DDPAG 411_ NSYLQ 416_ NVYAP 421_ EDDPE 426_ MKVER 431_ YKRTF 436_ DQNEE 441_ LGLND 446_ MKTEG 451_YEAGL
1: Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. It is involved in the positive regulation of cell cycle progression (PubMed:29851065). Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death