RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Dual specificity protein phosphatase 11) (Phosphatase that interacts with RNA/RNP complex 1)
1_MRNSE 6_ TLERG 11_ VGGCR 16_ VFSCL 21_ GSYPG 26_ IEGAG 31_ LALLA 36_ DLALG 41_ GRLLG 46_ THMSQ 51_ WHHPR 56_ SGWGR 61_ RRDFS 66_ GRSSA 71_ KKKGG 76_ NHIPE 81_ RWKDY 86_ LPVGQ 91_ RMPGT 96_ RFIAF 101_ KVPLQ 106_ KSFEK 111_ KLAPE 116_ ECFSP 121_ LDLFN 126_ KIREQ 131_ NEELG 136_ LIIDL 141_ TYTQR 146_ YYKPE 151_ DLPET 156_ VPYLK 161_ IFTVG 166_ HQVPD 171_ DETIF 176_ KFKHA 181_ VNGFL 186_ KENKD 191_ NDKLI 196_ GVHCT 201_ HGLNR 206_ TGYLI 211_ CRYLI 216_ DVEGV 221_ RPDDA 226_ IELFN 231_ RCRGH 236_ CLERQ 241_ NYIED 246_ LQNGP 251_ IRKNW 256_ NSSVP 261_ RSSDF 266_ EDSAH 271_ LMQPV 276_ HNKPV 281_ KQGPR 286_ YNLHQ 291_ IQGHS 296_ APRHF 301_ HTQTQ 306_ SLQQS 311_ VRKFS 316_ ENPHV 321_ YQRHH 326_ LPPPG 331_ PPGED 336_ YSHRR 341_ YSWNV 346_ KPNAS 351_ RAAQD 356_ RRRWY 361_ PYNYS 366_ RLSYP 371_ACWEW
1: Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism