Semaphorin-7A (CDw108) (JMH blood group antigen) (John-Milton-Hargen human blood group Ag) (Semaphorin-K1) (Sema K1) (Semaphorin-L) (Sema L) (CD antigen CD108)
1_MTPPP 6_ PGRAA 11_ PSAPR 16_ ARVPG 21_ PPARL 26_ GLPLR 31_ LRLLL 36_ LLWAA 41_ AASAQ 46_ GHLRS 51_ GPRIF 56_ AVWKG 61_ HVGQD 66_ RVDFG 71_ QTEPH 76_ TVLFH 81_ EPGSS 86_ SVWVG 91_ GRGKV 96_ YLFDF 101_ PEGKN 106_ ASVRT 111_ VNIGS 116_ TKGSC 121_ LDKRD 126_ CENYI 131_ TLLER 136_ RSEGL 141_ LACGT 146_ NARHP 151_ SCWNL 156_ VNGTV 161_ VPLGE 166_ MRGYA 171_ PFSPD 176_ ENSLV 181_ LFEGD 186_ EVYST 191_ IRKQE 196_ YNGKI 201_ PRFRR 206_ IRGES 211_ ELYTS 216_ DTVMQ 221_ NPQFI 226_ KATIV 231_ HQDQA 236_ YDDKI 241_ YYFFR 246_ EDNPD 251_ KNPEA 256_ PLNVS 261_ RVAQL 266_ CRGDQ 271_ GGESS 276_ LSVSK 281_ WNTFL 286_ KAMLV 291_ CSDAA 296_ TNKNF 301_ NRLQD 306_ VFLLP 311_ DPSGQ 316_ WRDTR 321_ VYGVF 326_ SNPWN 331_ YSAVC 336_ VYSLG 341_ DIDKV 346_ FRTSS 351_ LKGYH 356_ SSLPN 361_ PRPGK 366_ CLPDQ 371_ QPIPT 376_ ETFQV 381_ ADRHP 386_ EVAQR 391_ VEPMG 396_ PLKTP 401_ LFHSK 406_ YHYQK 411_ VAVHR 416_ MQASH 421_ GETFH 426_ VLYLT 431_ TDRGT 436_ IHKVV 441_ EPGEQ 446_ EHSFA 451_ FNIME 456_ IQPFR 461_ RAAAI 466_ QTMSL 471_ DAERR 476_ KLYVS 481_ SQWEV 486_ SQVPL 491_ DLCEV 496_ YGGGC 501_ HGCLM 506_ SRDPY 511_ CGWDQ 516_ GRCIS 521_ IYSSE 526_ RSVLQ 531_ SINPA 536_ EPHKE 541_ CPNPK 546_ PDKAP 551_ LQKVS 556_ LAPNS 561_ RYYLS 566_ CPMES 571_ RHATY 576_ SWRHK 581_ ENVEQ 586_ SCEPG 591_ HQSPN 596_ CILFI 601_ ENLTA 606_ QQYGH 611_ YFCEA 616_ QEGSY 621_ FREAQ 626_ HWQLL 631_ PEDGI 636_ MAEHL 641_ LGHAC 646_ ALAAS 651_ LWLGV 656_ LPTLT 661_LGLLV
1: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes