Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
1_MARMN 6_ RPAPV 11_ EVSYK 16_ HMRFL 21_ ITHNP 26_ TNATL 31_ STFIE 36_ DLKKY 41_ GATTV 46_ VRVCE 51_ VTYDK 56_ TPLEK 61_ DGITV 66_ VDWPF 71_ DDGAP 76_ PPGKV 81_ VEDWL 86_ SLVKA 91_ KFCEA 96_ PGSCV 101_ AVHCV 106_ AGLGR 111_ APVLV 116_ ALALI 121_ ESGMK 126_ YEDAI 131_ QFIRQ 136_ KRRGA 141_ INSKQ 146_ LTYLE 151_ KYRPK 156_ QRLRF 161_ KDPHT 166_HKTRC
1: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II