Probable G-protein coupled receptor 32
1_MNGVS 6_ EGTRG 11_ CSDRQ 16_ PGVLT 21_ RDRSC 26_ SRKMN 31_ SSGCL 36_ SEEVG 41_ SLRPL 46_ TVVIL 51_ SASIV 56_ VGVLG 61_ NGLVL 66_ WMTVF 71_ RMART 76_ VSTVC 81_ FFHLA 86_ LADFM 91_ LSLSL 96_ PIAMY 101_ YIVSR 106_ QWLLG 111_ EWACK 116_ LYITF 121_ VFLSY 126_ FASNC 131_ LLVFI 136_ SVDRC 141_ ISVLY 146_ PVWAL 151_ NHRTV 156_ QRASW 161_ LAFGV 166_ WLLAA 171_ ALCSA 176_ HLKFR 181_ TTRKW 186_ NGCTH 191_ CYLAF 196_ NSDNE 201_ TAQIW 206_ IEGVV 211_ EGHII 216_ GTIGH 221_ FLLGF 226_ LGPLA 231_ IIGTC 236_ AHLIR 241_ AKLLR 246_ EGWVH 251_ ANRPK 256_ RLLLV 261_ LVSAF 266_ FIFWS 271_ PFNVV 276_ LLVHL 281_ WRRVM 286_ LKEIY 291_ HPRML 296_ LILQA 301_ SFALG 306_ CVNSS 311_ LNPFL 316_ YVFVG 321_ RDFQE 326_ KFFQS 331_ LTSAL 336_ ARAFG 341_ EEEFL 346_ SSCPR 351_GNAPR
1: G-protein coupled receptor that binds to several ligands including resolvin D1 (RvD1) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. In macrophages, enhances the RvD1-stimulated phagocytic and clearance functions (PubMed:20080636). Macrophages migrate less toward different chemoattractant stimuli but phagocytose more microbial particles (PubMed:26969756). Prevents the increase in Ca(2+) and activation of ERK1/2 used by histamine and its H1 receptor subtype to induce goblet cell secretion by activating PKC and GRK2 to counter-regulate the histamine receptor (PubMed:23462912)