Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5)
1_MEDSD 6_ SAAKQ 11_ LGLAE 16_ AAAVA 21_ AAAAV 26_ AAAAA 31_ AAAGG 36_ EAEEP 41_ VLSRD 46_ EDSEE 51_ DADSE 56_ AERET 61_ PRVTA 66_ VAVMA 71_ AEPGH 76_ MDMGA 81_ EALPG 86_ PDEAA 91_ AAAAF 96_ AEVTT 101_ VTVAN 106_ VGAAA 111_ DNVFT 116_ TSVAN 121_ AASIS 126_ GHVLS 131_ GRTAL 136_ QIGDS 141_ LNTEK 146_ ATLIV 151_ VHTDG 156_ SIVET 161_ TGLKG 166_ PAAPL 171_ TPGPQ 176_ SPPTP 181_ LAPGQ 186_ EKGGT 191_ KYNWD 196_ PSVYD 201_ SELPV 206_ RCRNI 211_ SGTLY 216_ KNRLG 221_ SGGRG 226_ RCIKQ 231_ GENWY 236_ SPTEF 241_ EAMAG 246_ RASSK 251_ DWKRS 256_ IRYAG 261_ RPLQC 266_ LIQDG 271_ ILNPH 276_ AASCT 281_ CAACC 286_ DDMTL 291_ SGPVR 296_ LFVPY 301_ KRRKK 306_ ENELP 311_ TTPVK 316_ KDSPK 321_ NITLL 326_ PATAA 331_ TTFTV 336_ TPSGQ 341_ ITTSG 346_ ALTFD 351_ RASTV 356_ EATAV 361_ ISESP 366_ AQGDV 371_ FAGAT 376_ VQEAS 381_ VQPPC 386_ RASHP 391_ EPHYP 396_ GYQDS 401_ CQIAP 406_ FPEAA 411_ LPTSH 416_ PKIVL 421_ TSLPA 426_ LAVPP 431_ PTPTK 436_ AAPPA 441_ LVNGL 446_ ELSEP 451_ RSWLY 456_ LEEMV 461_ NSLLN 466_ TAQQL 471_ KTLFE 476_ QAKHA 481_ STYRE 486_ AATNQ 491_ AKIHA 496_ DAERK 501_ EQSCV 506_ NCGRE 511_ AMSEC 516_ TGCHK 521_ VNYCS 526_ TFCQR 531_ KDWKD 536_ HQHIC 541_ GQSAA 546_ VTVQA 551_ DEVHV 556_AESVM
1: Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3