Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (P-52)
1_MAAAA 6_ ARVVL 11_ SSAAR 16_ RRLWG 21_ FSESL 26_ LIRGA 31_ AGRSL 36_ YFGEN 41_ RLRST 46_ QAATQ 51_ VVLNV 56_ PETRV 61_ TCLES 66_ GLRVA 71_ SEDSG 76_ LSTCT 81_ VGLWI 86_ DAGSR 91_ YENEK 96_ NNGTA 101_ HFLEH 106_ MAFKG 111_ TKKRS 116_ QLDLE 121_ LEIEN 126_ MGAHL 131_ NAYTS 136_ REQTV 141_ YYAKA 146_ FSKDL 151_ PRAVE 156_ ILADI 161_ IQNST 166_ LGEAE 171_ IERER 176_ GVILR 181_ EMQEV 186_ ETNLQ 191_ EVVFD 196_ YLHAT 201_ AYQNT 206_ ALGRT 211_ ILGPT 216_ ENIKS 221_ ISRKD 226_ LVDYI 231_ TTHYK 236_ GPRIV 241_ LAAAG 246_ GVSHD 251_ ELLDL 256_ AKFHF 261_ GDSLC 266_ THKGE 271_ IPALP 276_ PCKFT 281_ GSEIR 286_ VRDDK 291_ MPLAH 296_ LAIAV 301_ EAVGW 306_ AHPDT 311_ ICLMV 316_ ANTLI 321_ GNWDR 326_ SFGGG 331_ MNLSS 336_ KLAQL 341_ TCHGN 346_ LCHSF 351_ QSFNT 356_ SYTDT 361_ GLWGL 366_ YMVCE 371_ SSTVA 376_ DMLHV 381_ VQKEW 386_ MRLCT 391_ SVTES 396_ EVARA 401_ RNLLK 406_ TNMLL 411_ QLDGS 416_ TPICE 421_ DIGRQ 426_ MLCYN 431_ RRIPI 436_ PELEA 441_ RIDAV 446_ NAETI 451_ REVCT 456_ KYIYN 461_ RSPAI 466_ AAVGP 471_ IKQLP 476_ DFKQI 481_RSNMC
1: Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable) (PubMed:29576218). Preferentially, cleaves after an arginine at position P2 (By similarity). Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis (PubMed:22354088)