Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25)
1_MAKER 6_ RRAVL 11_ ELLQR 16_ PGNAR 21_ CADCG 26_ APDPD 31_ WASYT 36_ LGVFI 41_ CLSCS 46_ GIHRN 51_ IPQVS 56_ KVKSV 61_ RLDAW 66_ EEAQV 71_ EFMAS 76_ HGNDA 81_ ARARF 86_ ESKVP 91_ SFYYR 96_ PTPSD 101_ CQLLR 106_ EQWIR 111_ AKYER 116_ QEFIY 121_ PEKQE 126_ PYSAG 131_ YREGF 136_ LWKRG 141_ RDNGQ 146_ FLSRK 151_ FVLTE 156_ REGAL 161_ KYFNR 166_ NDAKE 171_ PKAVM 176_ KIEHL 181_ NATFQ 186_ PAKIG 191_ HPHGL 196_ QVTYL 201_ KDNST 206_ RNIFI 211_ YHEDG 216_ KEIVD 221_ WFNAL 226_ RAARF 231_ HYLQV 236_ AFPGA 241_ GDADL 246_ VPKLS 251_ RNYLK 256_ EGYME 261_ KTGPK 266_ QTEGF 271_ RKRWF 276_ TMDDR 281_ RLMYF 286_ KDPLD 291_ AFARG 296_ EVFIG 301_ SKESG 306_ YTVLH 311_ GFPPS 316_ TQGHH 321_ WPHGI 326_ TIVTP 331_ DRKFL 336_ FACET 341_ ESDQR 346_ EWVAA 351_ FQKAV 356_ DRPML 361_ PQEYA 366_VEAHF
1: GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Regulates the incorporation of CD63 and CD9 into multivesicular bodies (PubMed:38682696)