Leukocyte cell-derived chemotaxin 1 (Chondromodulin) [Cleaved into: Chondrosurfactant protein (CH-SP); Chondromodulin-1 (Chondromodulin-I) (ChM-I)]
1_MTENS 6_ DKVPI 11_ ALVGP 16_ DDVEF 21_ CSPPA 26_ YATLT 31_ VKPSS 36_ PARLL 41_ KVGAV 46_ VLISG 51_ AVLLL 56_ FGAIG 61_ AFYFW 66_ KGSDS 71_ HIYNV 76_ HYTMS 81_ INGKL 86_ QDGSM 91_ EIDAG 96_ NNLET 101_ FKMGS 106_ GAEEA 111_ IAVND 116_ FQNGI 121_ TGIRF 126_ AGGEK 131_ CYIKA 136_ QVKAR 141_ IPEVG 146_ AVTKQ 151_ SISSK 156_ LEGKI 161_ MPVKY 166_ EENSL 171_ IWVAV 176_ DQPVK 181_ DNSFL 186_ SSKVL 191_ ELCGD 196_ LPIFW 201_ LKPTY 206_ PKEIQ 211_ RERRE 216_ VVRKI 221_ VPTTT 226_ KRPHS 231_ GPRSN 236_ PGAGR 241_ LNNET 246_ RPSVQ 251_ EDSQA 256_ FNPDN 261_ PYHQQ 266_ EGESM 271_ TFDPR 276_ LDHEG 281_ ICCIE 286_ CRRSY 291_ THCQK 296_ ICEPL 301_ GGYYP 306_ WPYNY 311_ QGCRS 316_ ACRVI 321_ MPCSW 326_WVARI
1: Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization