Protein SCO1 homolog, mitochondrial
1_MAMLV 6_ LVPGR 11_ VMRPL 16_ GGQLW 21_ RFLPR 26_ GLEFW 31_ GPAEG 36_ TARVL 41_ LRQFC 46_ ARQAE 51_ AWRAS 56_ GRPGY 61_ CLGTR 66_ PLSTA 71_ RPPPP 76_ WSQKG 81_ PGDST 86_ RPSKP 91_ GPVSW 96_ KSLAI 101_ TFAIG 106_ GALLA 111_ GMKHV 116_ KKEKA 121_ EKLEK 126_ ERQRH 131_ IGKPL 136_ LGGPF 141_ SLTTH 146_ TGERK 151_ TDKDY 156_ LGQWL 161_ LIYFG 166_ FTHCP 171_ DVCPE 176_ ELEKM 181_ IQVVD 186_ EIDSI 191_ TTLPD 196_ LTPLF 201_ ISIDP 206_ ERDTK 211_ EAIAN 216_ YVKEF 221_ SPKLV 226_ GLTGT 231_ REEVD 236_ QVARA 241_ YRVYY 246_ SPGPK 251_ DEDED 256_ YIVDH 261_ TIIMY 266_ LIGPD 271_ GEFLD 276_ YFGQN 281_ KRKGE 286_ IAASI 291_ ATHMR 296_PYRKK
1: Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 (PubMed:15229189, PubMed:15659396, PubMed:16735468, PubMed:17189203, PubMed:19336478). Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (By similarity)