Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1)
1_MKIAV 6_ IGQSL 11_ FGQEV 16_ YCHLR 21_ KEGHE 26_ VVGVF 31_ TVPDK 36_ DGKAD 41_ PLGLE 46_ AEKDG 51_ VPVFK 56_ YSRWR 61_ AKGQA 66_ LPDVV 71_ AKYQA 76_ LGAEL 81_ NVLPF 86_ CSQFI 91_ PMEII 96_ SAPRH 101_ GSIIY 106_ HPSLL 111_ PRHRG 116_ ASAIN 121_ WTLIH 126_ GDKKG 131_ GFSIF 136_ WADDG 141_ LDTGD 146_ LLLQK 151_ ECEVL 156_ PDDTV 161_ STLYN 166_ RFLFP 171_ EGIKG 176_ MVQAV 181_ RLIAE 186_ GKAPR 191_ LPQPE 196_ EGATY 201_ EGIQK 206_ KETAK 211_ INWDQ 216_ PAEAI 221_ HNWIR 226_ GNDKV 231_ PGAWT 236_ EACEQ 241_ KLTFF 246_ NSTLN 251_ TSGLV 256_ PEGDA 261_ LPIPG 266_ AHRPG 271_ VVTKA 276_ GLILF 281_ GNDDK 286_ MLLVK 291_ NIQLE 296_ DGKMI 301_ LASNF 306_ FKGAA 311_ SSVLE 316_ LTEAE 321_ LVTAE 326_ AVRSV 331_ WQRIL 336_ PKVLE 341_ VEDST 346_ DFFKS 351_ GAASV 356_ DVVRL 361_ VEEVK 366_ ELCDG 371_ LELEN 376_ EDVYM 381_ ASTFG 386_ DFIQL 391_ LVRKL 396_ RGDDE 401_ EGECS 406_ IDYVE 411_ MAVNK 416_ RTVRM 421_ PHQLF 426_ IGGEF 431_ VDAEG 436_ AKTSE 441_ TINPT 446_ DGSVI 451_ CQVSL 456_ AQVTD 461_ VDKAV 466_ AAAKD 471_ AFENG 476_ RWGKI 481_ SARDR 486_ GRLMY 491_ RLADL 496_ MEQHQ 501_ EELAT 506_ IEALD 511_ AGAVY 516_ TLALK 521_ THVGM 526_ SIQTF 531_ RYFAG 536_ WCDKI 541_ QGSTI 546_ PINQA 551_ RPNRN 556_ LTLTR 561_ KEPVG 566_ VCGII 571_ IPWNY 576_ PLMML 581_ SWKTA 586_ ACLAA 591_ GNTVV 596_ IKPAQ 601_ VTPLT 606_ ALKFA 611_ ELTLK 616_ AGIPK 621_ GVVNV 626_ LPGSG 631_ SLVGQ 636_ RLSDH 641_ PDVRK 646_ IGFTG 651_ STEVG 656_ KHIMK 661_ SCAIS 666_ NVKKV 671_ SLELG 676_ GKSPL 681_ IIFAD 686_ CDLNK 691_ AVQMG 696_ MSSVF 701_ FNKGE 706_ NCIAA 711_ GRLFV 716_ EDSIH 721_ DEFVR 726_ RVVEE 731_ VRKMK 736_ VGNPL 741_ DRDTD 746_ HGPQN 751_ HHAHL 756_ VKLME 761_ YCQHG 766_ VKEGA 771_ TLVCG 776_ GNQVP 781_ RPGFF 786_ FEPTV 791_ FTDVE 796_ DHMFI 801_ AKEES 806_ FGPVM 811_ IISRF 816_ ADGDL 821_ DAVLS 826_ RANAT 831_ EFGLA 836_ SGVFT 841_ RDINK 846_ ALYVS 851_ DKLQA 856_ GTVFV 861_ NTYNK 866_ TDVAA 871_ PFGGF 876_ KQSGF 881_ GKDLG 886_ EAALN 891_ EYLRV 896_KTVTF
1: Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436). May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde (By similarity)