Gene name: SERF1A

Uniprot entry:

O75920

Protein names:

Small EDRK-rich factor 1 (Protein 4F5) (h4F5) (SMA modifier 1)

Protein sequence:

1_MARGN 6_ QRELA 11_ RQKNM 16_ KKTQE 21_ ISKGK 26_ RKEDS 31_ LTASQ 36_ RKQSS 41_ GGQKS 46_ ESKMS 51_ AGPHL 56_ PLKAP 61_ RENPC 66_ FPLPA 71_ AGGSR 76_ YYLAY 81_ GSITP 86_ ISAFV 91_ FVVFF 96_ SVFFP 101_SFYED

Protein annotations

Protein functions:

1: Positive regulator of amyloid protein aggregation and proteotoxicity (PubMed:20723760, PubMed:22854022, PubMed:31034892). Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates (PubMed:20723760, PubMed:22854022, PubMed:31034892)