ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d)
1_MAGRK 6_ LALKT 11_ IDWVA 16_ FAEII 21_ PQNQK 26_ AIASS 31_ LKSWN 36_ ETLTS 41_ RLAAL 46_ PENPP 51_ AIDWA 56_ YYKAN 61_ VAKAG 66_ LVDDF 71_ EKKFN 76_ ALKVP 81_ VPEDK 86_ YTAQV 91_ DAEEK 96_ EDVKS 101_ CAEWV 106_ SLSKA 111_ RIVEY 116_ EKEME 121_ KMKNL 126_ IPFDQ 131_ MTIED 136_ LNEAF 141_ PETKL 146_ DKKKY 151_ PYWPH 156_QPIEN
1: Subunit d, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (PubMed:37244256). Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity)