Dolichol phosphate-mannose biosynthesis regulatory protein (Dolichol-phosphate mannose synthase subunit 2) (DPM synthase subunit 2)
1_MATGT 6_ DQVVG 11_ LGLVA 16_ VSLII 21_ FTYYT 26_ AWVIL 31_ LPFID 36_ SQHVI 41_ HKYFL 46_ PRAYA 51_ VAIPL 56_ AAGLL 61_ LLLFV 66_ GLFIS 71_ YVMLK 76_TKRVT
1: Regulates the biosynthesis of dolichol phosphate-mannose (PubMed:10835346). Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1 (PubMed:10835346). Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis (PubMed:16162815). May act by regulating the GPI-GNT complex (PubMed:10944123)