E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (RING-type E3 ubiquitin transferase listerin) (Zinc finger protein 294)
1_MGGKN 6_ KQRTK 11_ GNLRP 16_ SNSGR 21_ AAELL 26_ AKEQG 31_ TVPGF 36_ IGFGT 41_ SQSDL 46_ GYVPA 51_ IQGAE 56_ EIDSL 61_ VDSDF 66_ RMVLR 71_ KLSKK 76_ DVTTK 81_ LKAMQ 86_ EFGTM 91_ CTERD 96_ TETVK 101_ GVLPY 106_ WPRIF 111_ CKISL 116_ DHDRR 121_ VREAT 126_ QQAFE 131_ KLILK 136_ VKKQL 141_ APYLK 146_ SLMGY 151_ WLMAQ 156_ CDTYT 161_ PAAFA 166_ AKDAF 171_ EAAFP 176_ PSKQP 181_ EAIAF 186_ CKDEI 191_ TSVLQ 196_ DHLIK 201_ ETPDT 206_ LSDPQ 211_ TVPEE 216_ EREAK 221_ FYRVV 226_ TCSLL 231_ ALKRL 236_ LCLLP 241_ DNELD 246_ SLEEK 251_ FKSLL 256_ SQNKF 261_ WKYGK 266_ HSVPQ 271_ IRSAY 276_ FELVS 281_ ALCQR 286_ IPQLM 291_ KEEAS 296_ KVSPS 301_ VLLSI 306_ DDSDP 311_ IVCPA 316_ LWEAV 321_ LYTLT 326_ TIEDC 331_ WLHVN 336_ AKKSV 341_ FPKLS 346_ TVIRE 351_ GGRGL 356_ ATVIY 361_ PYLLP 366_ FISKL 371_ PQSIT 376_ NPKLD 381_ FFKNF 386_ LTSLV 391_ AGLST 396_ ERTKT 401_ SSLES 406_ SAVIS 411_ AFFEC 416_ LRFIM 421_ QQNLG 426_ EEEIE 431_ QMLVN 436_ DQLIP 441_ FIDAV 446_ LKDPG 451_ LQHGQ 456_ LFNHL 461_ AETLS 466_ SWEAK 471_ ADTEK 476_ DEKTA 481_ HNLEN 486_ VLIHF 491_ WERLS 496_ EICVA 501_ KISEP 506_ EADVE 511_ SVLGV 516_ SNLLQ 521_ VLQKP 526_ KSSLK 531_ SSKKK 536_ NGKVR 541_ FADEI 546_ LESNK 551_ ENEKC 556_ VSSEG 561_ EKIEG 566_ WELTT 571_ EPSLT 576_ HNSSG 581_ LLSPL 586_ RKKPL 591_ EDLVC 596_ KLADI 601_ SINYV 606_ NERKS 611_ EQHLR 616_ FLSTL 621_ LDSFS 626_ SSRVF 631_ KMLLG 636_ DEKQS 641_ IVQAK 646_ PLEIA 651_ KLVQK 656_ NPAVQ 661_ FLYQK 666_ LIGWL 671_ NEDQR 676_ KDFGF 681_ LVDIL 686_ YSALR 691_ CCDND 696_ MERKK 701_ VLDDL 706_ TKVDL 711_ KWNSL 716_ LKIIE 721_ KACPS 726_ SDKHA 731_ LVTPW 736_ LKGDI 741_ LGEKL 746_ VNLAD 751_ CLCNE 756_ DLESR 761_ VSSES 766_ HFSER 771_ WTLLS 776_ LVLSQ 781_ HVKND 786_ YLIGD 791_ VYVER 796_ IIVRL 801_ HETLF 806_ KTKKL 811_ SEAES 816_ SDSSV 821_ SFICD 826_ VAYNY 831_ FSSAK 836_ GCLLM 841_ PSSED 846_ LLLTL 851_ FQLCA 856_ QSKEK 861_ THLPD 866_ FLICK 871_ LKNTW 876_ LSGVN 881_ LLVHQ 886_ TDSSY 891_ KESTF 896_ LHLSA 901_ LWLKN 906_ QVQAS 911_ SLDIN 916_ SLQVL 921_ LSAVD 926_ DLLNT 931_ LLESE 936_ DSYLM 941_ GVYIG 946_ SVMPN 951_ DSEWE 956_ KMRQS 961_ LPMQW 966_ LHRPL 971_ LEGRL 976_ SLNYE 981_ CFKTD 986_ FKEQD 991_ IKTLP 996_ SHLCT 1001_ SALLS 1006_ KMVLI 1011_ ALRKE 1016_ TVLEN 1021_ NELEK 1026_ IIAEL 1031_ LYSLQ 1036_ WCEEL 1041_ DNPPI 1046_ FLIGF 1051_ CEILQ 1056_ KMNIT 1061_ YDNLR 1066_ VLGNT 1071_ SGLLQ 1076_ LLFNR 1081_ SREHG 1086_ TLWSL 1091_ IIAKL 1096_ ILSRS 1101_ ISSDE 1106_ VKPHY 1111_ KRKES 1116_ FFPLT 1121_ EGNLH 1126_ TIQSL 1131_ CPFLS 1136_ KEEKK 1141_ EFSAQ 1146_ CIPAL 1151_ LGWTK 1156_ KDLCS 1161_ TNGGF 1166_ GHLAI 1171_ FNSCL 1176_ QTKSI 1181_ DDGEL 1186_ LHGIL 1191_ KIIIS 1196_ WKKEH 1201_ EDIFL 1206_ FSCNL 1211_ SEASP 1216_ EVLGV 1221_ NIEII 1226_ RFLSL 1231_ FLKYC 1236_ SSPLA 1241_ ESEWD 1246_ FIMCS 1251_ MLAWL 1256_ ETTSE 1261_ NQALY 1266_ SIPLV 1271_ QLFAC 1276_ VSCDL 1281_ ACDLS 1286_ AFFDS 1291_ TTLDT 1296_ IGNLP 1301_ VNLIS 1306_ EWKEF 1311_ FSQGI 1316_ HSLLL 1321_ PILVT 1326_ VTGEN 1331_ KDVSE 1336_ TSFQN 1341_ AMLKP 1346_ MCETL 1351_ TYISK 1356_ EQLLS 1361_ HKLPA 1366_ RLVAD 1371_ QKTNL 1376_ PEYLQ 1381_ TLLNT 1386_ LAPLL 1391_ LFRAR 1396_ PVQIA 1401_ VYHML 1406_ YKLMP 1411_ ELPQY 1416_ DQDNL 1421_ KSYGD 1426_ EEEEP 1431_ ALSPP 1436_ AALMS 1441_ LLSIQ 1446_ EDLLE 1451_ NVLGC 1456_ IPVGQ 1461_ IVTIK 1466_ PLSED 1471_ FCYVL 1476_ GYLLT 1481_ WKLIL 1486_ TFFKA 1491_ ASSQL 1496_ RALYS 1501_ MYLRK 1506_ TKSLN 1511_ KLLYH 1516_ LFRLM 1521_ PENPT 1526_ YAETA 1531_ VEVPN 1536_ KDPKT 1541_ FFTEE 1546_ LQLSI 1551_ RETTM 1556_ LPYHI 1561_ PHLAC 1566_ SVYHM 1571_ TLKDL 1576_ PAMVR 1581_ LWWNS 1586_ SEKRV 1591_ FNIVD 1596_ RFTSK 1601_ YVSSV 1606_ LSFQE 1611_ ISSVQ 1616_ TSTQL 1621_ FNGMT 1626_ VKARA 1631_ TTREV 1636_ MATYT 1641_ IEDIV 1646_ IELII 1651_ QLPSN 1656_ YPLGS 1661_ IIVES 1666_ GKRVG 1671_ VAVQQ 1676_ WRNWM 1681_ LQLST 1686_ YLTHQ 1691_ NGSIM 1696_ EGLAL 1701_ WKNNV 1706_ DKRFE 1711_ GVEDC 1716_ MICFS 1721_ VIHGF 1726_ NYSLP 1731_ KKACR 1736_ TCKKK 1741_ FHSAC 1746_ LYKWF 1751_ TSSNK 1756_ STCPL 1761_CRETF
1: E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875, PubMed:28757607). Within the RQC complex, LTN1 is recruited to stalled 60S ribosomal subunits by NEMF and mediates ubiquitination of stalled nascent chains (PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity)