TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
1_MEFPG 6_ GNDNY 11_ LTITG 16_ PSHPF 21_ LSGAE 26_ TFHTP 31_ SLGDE 36_ EFEIP 41_ PISLD 46_ SDPSL 51_ AVSDV 56_ VGHFD 61_ DLADP 66_ SSSQD 71_ GSFSA 76_ QYGVQ 81_ TLDMP 86_ VGMTH 91_ GLMEQ 96_ GGGLL 101_ SGGLT 106_ MDLDH 111_ SIGTQ 116_ YSANP 121_ PVTID 126_ VPMTD 131_ MTSGL 136_ MGHSQ 141_ LTTID 146_ QSELS 151_ SQLGL 156_ SLGGG 161_ TILPP 166_ AQSPE 171_ DRLST 176_ TPSPT 181_ SSLHE 186_ DGVED 191_ FRRQL 196_ PSQKT 201_ VVVEA 206_ GKKQK 211_ APKKR 216_ KKKDP 221_ NEPQK 226_ PVSAY 231_ ALFFR 236_ DTQAA 241_ IKGQN 246_ PNATF 251_ GEVSK 256_ IVASM 261_ WDSLG 266_ EEQKQ 271_ VYKRK 276_ TEAAK 281_ KEYLK 286_ ALAAY 291_ KDNQE 296_ CQATV 301_ ETVEL 306_ DPAPP 311_ SQTPS 316_ PPPMA 321_ TVDPA 326_ SPAPA 331_ SIEPP 336_ ALSPS 341_ IVVNS 346_ TLSSY 351_ VANQA 356_ SSGAG 361_ GQPNI 366_ TKLII 371_ TKQML 376_ PSSIT 381_ MSQGG 386_ MVTVI 391_ PATVV 396_ TSRGL 401_ QLGQT 406_ STATI 411_ QPSQQ 416_ AQIVT 421_ RSVLQ 426_ AAAAA 431_ AAAAS 436_ MQLPP 441_ PRLQP 446_ PPLQQ 451_ MPQPP 456_ TQQQV 461_ TILQQ 466_ PPPLQ 471_ AMQQP 476_ PPQKV 481_ RINLQ 486_ QQPPP 491_ LQIKS 496_ VPLPT 501_ LKMQT 506_ TLVPP 511_ TVESS 516_ PERPM 521_ NNSPE 526_ AHTVE 531_ APSPE 536_ TICEM 541_ ITDVV 546_ PEVES 551_ PSQMD 556_ VELVS 561_ GSPVA 566_ LSPQP 571_ RCVRS 576_ GCENP 581_ PIVSK 586_ DWDNE 591_ YCSNE 596_ CVVKH 601_ CRDVF 606_ LAWVA 611_ SRNSN 616_TVVFV
1: Transcription factor that modulates cell fate reprogramming from the somatic state to the pluripotent and neuronal fate (By similarity). In liver, controls the expression of hormone-regulated gluconeogenic genes such as G6PC1 and PCK1 (By similarity). This regulation is independent of the insulin receptor activation (By similarity). Also acts as a regulatory component of protein phosphatase 1 (PP1) complexes (PubMed:39603239, PubMed:39603240). Component of the PNUTS-PP1 protein phosphatase complex, a PP1 complex that regulates RNA polymerase II transcription pause-release (PubMed:39603239, PubMed:39603240). PNUTS-PP1 also plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase (PubMed:20516061)