PHD finger protein 14
1_MDRSS 6_ KRRQV 11_ KPLAA 16_ SLLEA 21_ LDYDS 26_ SDDSD 31_ FKVGD 36_ ASDSE 41_ GSGNG 46_ SEDAS 51_ KDSGE 56_ GSCSD 61_ SEENI 66_ LEEEL 71_ NEDIK 76_ VKEEQ 81_ LKNSA 86_ EEEVL 91_ SSEKQ 96_ LIKME 101_ KKEEE 106_ ENGER 111_ PRKKK 116_ EKEKE 121_ KEKEK 126_ EKEKE 131_ REKEK 136_ EKATV 141_ SENVA 146_ ASAAA 151_ TTPAT 156_ SPPAV 161_ NTSPS 166_ VPTTT 171_ TATEE 176_ QVSEP 181_ KKWNL 186_ RRNRP 191_ LLDFV 196_ SMEEL 201_ NDMDD 206_ YDSED 211_ DNDWR 216_ PTVVK 221_ RKGRS 226_ ASQKE 231_ GSDGD 236_ NEDDE 241_ DEGSG 246_ SDEDE 251_ NDEGN 256_ DEDHS 261_ SPASE 266_ GGCKK 271_ KKSKV 276_ LSRNS 281_ ADDEE 286_ LTNDS 291_ LTLSQ 296_ SKSNE 301_ DSLIL 306_ EKSQN 311_ WSSQK 316_ MDHIL 321_ ICCVC 326_ LGDNS 331_ EDADE 336_ IIQCD 341_ NCGIT 346_ VHEGC 351_ YGVDG 356_ ESDSI 361_ MSSAS 366_ ENSTE 371_ PWFCD 376_ ACKCG 381_ VSPSC 386_ ELCPN 391_ QDGIF 396_ KETDA 401_ GRWVH 406_ IVCAL 411_ YVPGV 416_ AFGDI 421_ DKLRP 426_ VTLTE 431_ MNYSK 436_ YGAKE 441_ CSFCE 446_ DPRFA 451_ RTGVC 456_ ISCDA 461_ GMCRA 466_ YFHVT 471_ CAQKE 476_ GLLSE 481_ AAAEE 486_ DIADP 491_ FFAYC 496_ KQHAD 501_ RLDRK 506_ WKRKN 511_ YLALQ 516_ SYCKM 521_ SLQER 526_ EKQLS 531_ PEAQA 536_ RINAR 541_ LQQYR 546_ AKAEL 551_ ARSTR 556_ PQAWV 561_ PREKL 566_ PRPLT 571_ SSASA 576_ IRKLM 581_ RKAEL 586_ MGIST 591_ DIFPV 596_ DNSDT 601_ SSSVD 606_ GRRKH 611_ KQPAL 616_ TADFV 621_ NYYFE 626_ RNMRM 631_ IQIQE 636_ NMAEQ 641_ KNIKD 646_ KLENE 651_ QEKLH 656_ VEYNK 661_ LCESL 666_ EELQN 671_ LNGKL 676_ RSEGQ 681_ GIWAL 686_ LGRIT 691_ GQKLN 696_ IPAIL 701_ RAPKE 706_ RKPSK 711_ KEGGT 716_ QKTST 721_ LPAVL 726_ YSCGI 731_ CKKNH 736_ DQHLL 741_ LLCDT 746_ CKLHY 751_ HLGCL 756_ DPPLT 761_ RMPRK 766_ TKNSY 771_ WQCSE 776_ CDQAG 781_ SSDME 786_ ADMAM 791_ ETLPD 796_ GTKRS 801_ RRQIK 806_ EPVKF 811_ VPQDV 816_ PPEPK 821_ KIPIR 826_ NTRTR 831_ GRKRS 836_ FVPEE 841_ EKHEE 846_ RVPRE 851_ RRQRQ 856_ SVLQK 861_ KPKAE 866_ DLRTE 871_ CATCK 876_ GTGDN 881_ENLVR
1: Histone-binding protein (PubMed:23688586). Binds preferentially to unmodified histone H3 but can also bind to a lesser extent to histone H3 trimethylated at 'Lys-9' (H3K9me3) as well as to histone H3 monomethylated at 'Lys-27' (H3K27ac) and trimethylated at 'Lys-27' (H3K27me3) (By similarity). Represses PDGFRA expression, thus playing a role in regulation of mesenchymal cell proliferation (By similarity). Suppresses the expression of CDKN1A/p21 by reducing the level of trimethylation of histone H3 'Lys-4', leading to enhanced proliferation of germinal center B cells (By similarity)