Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
1_MNKKK 6_ KPFLG 11_ MPAPL 16_ GYVPG 21_ LGRGA 26_ TGFTT 31_ RSDIG 36_ PARDA 41_ NDPVD 46_ DRHAP 51_ PGKRT 56_ VGDQM 61_ KKNQA 66_ ADDDD 71_ EDLND 76_ TNYDE 81_ FNGYA 86_ GSLFS 91_ SGPYE 96_ KDDEE 101_ ADAIY 106_ AALDK 111_ RMDER 116_ RKERR 121_ EQREK 126_ EEIEK 131_ YRMER 136_ PKIQQ 141_ QFSDL 146_ KRKLA 151_ EVTEE 156_ EWLSI 161_ PEVGD 166_ ARNKR 171_ QRNPR 176_ YEKLT 181_ PVPDS 186_ FFAKH 191_ LQTGE 196_ NHTSV 201_ DPRQT 206_ QFGGL 211_ NTPYP 216_ GGLNT 221_ PYPGG 226_ MTPGL 231_ MTPGT 236_ GELDM 241_ RKIGQ 246_ ARNTL 251_ MDMRL 256_ SQVSD 261_ SVSGQ 266_ TVVDP 271_ KGYLT 276_ DLNSM 281_ IPTHG 286_ GDIND 291_ IKKAR 296_ LLLKS 301_ VRETN 306_ PHHPP 311_ AWIAS 316_ ARLEE 321_ VTGKL 326_ QVARN 331_ LIMKG 336_ TEMCP 341_ KSEDV 346_ WLEAA 351_ RLQPG 356_ DTAKA 361_ VVAQA 366_ VRHLP 371_ QSVRI 376_ YIRAA 381_ ELETD 386_ IRAKK 391_ RVLRK 396_ ALEHV 401_ PNSVR 406_ LWKAA 411_ VELEE 416_ PEDAR 421_ IMLSR 426_ AVECC 431_ PTSVE 436_ LWLAL 441_ ARLET 446_ YENAR 451_ KVLNK 456_ ARENI 461_ PTDRH 466_ IWITA 471_ AKLEE 476_ ANGNT 481_ QMVEK 486_ IIDRA 491_ ITSLR 496_ ANGVE 501_ INREQ 506_ WIQDA 511_ EECDR 516_ AGSVA 521_ TCQAV 526_ MRAVI 531_ GIGIE 536_ EEDRK 541_ HTWME 546_ DADSC 551_ VAHNA 556_ LECAR 561_ AIYAY 566_ ALQVF 571_ PSKKS 576_ VWLRA 581_ AYFEK 586_ NHGTR 591_ ESLEA 596_ LLQRA 601_ VAHCP 606_ KAEVL 611_ WLMGA 616_ KSKWL 621_ AGDVP 626_ AARSI 631_ LALAF 636_ QANPN 641_ SEEIW 646_ LAAVK 651_ LESEN 656_ DEYER 661_ ARRLL 666_ AKARS 671_ SAPTA 676_ RVFMK 681_ SVKLE 686_ WVQDN 691_ IRAAQ 696_ DLCEE 701_ ALRHY 706_ EDFPK 711_ LWMMK 716_ GQIEE 721_ QKEMM 726_ EKARE 731_ AYNQG 736_ LKKCP 741_ HSTPL 746_ WLLLS 751_ RLEEK 756_ IGQLT 761_ RARAI 766_ LEKSR 771_ LKNPK 776_ NPGLW 781_ LESVR 786_ LEYRA 791_ GLKNI 796_ ANTLM 801_ AKALQ 806_ ECPNS 811_ GILWS 816_ EAIFL 821_ EARPQ 826_ RRTKS 831_ VDALK 836_ KCEHD 841_ PHVLL 846_ AVAKL 851_ FWSQR 856_ KITKA 861_ REWFH 866_ RTVKI 871_ DSDLG 876_ DAWAF 881_ FYKFE 886_ LQHGT 891_ EEQQE 896_ EVRKR 901_ CESAE 906_ PRHGE 911_ LWCAV 916_ SKDIA 921_ NWQKK 926_ IGDIL 931_ RLVAG 936_RIKNT
1: Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:20118938, PubMed:21549338, PubMed:28781166). Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation