Tumor necrosis factor ligand superfamily member 15 (TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor) [Cleaved into: Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form]
1_MAEDL 6_ GLSFG 11_ ETASV 16_ EMLPE 21_ HGSCR 26_ PKARS 31_ SSARW 36_ ALTCC 41_ LVLLP 46_ FLAGL 51_ TTYLL 56_ VSQLR 61_ AQGEA 66_ CVQFQ 71_ ALKGQ 76_ EFAPS 81_ HQQVY 86_ APLRA 91_ DGDKP 96_ RAHLT 101_ VVRQT 106_ PTQHF 111_ KNQFP 116_ ALHWE 121_ HELGL 126_ AFTKN 131_ RMNYT 136_ NKFLL 141_ IPESG 146_ DYFIY 151_ SQVTF 156_ RGMTS 161_ ECSEI 166_ RQAGR 171_ PNKPD 176_ SITVV 181_ ITKVT 186_ DSYPE 191_ PTQLL 196_ MGTKS 201_ VCEVG 206_ SNWFQ 211_ PIYLG 216_ AMFSL 221_ QEGDK 226_ LMVNV 231_ SDISL 236_ VDYTK 241_ EDKTF 246_FGAFL
1: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis