Gene name: SPDEF

Uniprot entry:

O95238

Protein names:

SAM pointed domain-containing Ets transcription factor (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets) (Prostate-derived Ets factor)

Protein sequence:

1_MGSAS 6_ PGLSS 11_ VSPSH 16_ LLLPP 21_ DTVSR 26_ TGLEK 31_ AAAGA 36_ VGLER 41_ RDWSP 46_ SPPAT 51_ PEQGL 56_ SAFYL 61_ SYFDM 66_ LYPED 71_ SSWAA 76_ KAPGA 81_ SSREE 86_ PPEEP 91_ EQCPV 96_ IDSQA 101_ PAGSL 106_ DLVPG 111_ GLTLE 116_ EHSLE 121_ QVQSM 126_ VVGEV 131_ LKDIE 136_ TACKL 141_ LNITA 146_ DPMDW 151_ SPSNV 156_ QKWLL 161_ WTEHQ 166_ YRLPP 171_ MGKAF 176_ QELAG 181_ KELCA 186_ MSEEQ 191_ FRQRS 196_ PLGGD 201_ VLHAH 206_ LDIWK 211_ SAAWM 216_ KERTS 221_ PGAIH 226_ YCAST 231_ SEESW 236_ TDSEV 241_ DSSCS 246_ GQPIH 251_ LWQFL 256_ KELLL 261_ KPHSY 266_ GRFIR 271_ WLNKE 276_ KGIFK 281_ IEDSA 286_ QVARL 291_ WGIRK 296_ NRPAM 301_ NYDKL 306_ SRSIR 311_ QYYKK 316_ GIIRK 321_ PDISQ 326_RLVYQ

Protein annotations

Protein functions:

1: May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter