Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)
1_MAAGT 6_ SSYWE 11_ DLRKQ 16_ ARQLE 21_ NELDL 26_ KLVSF 31_ SKLCT 36_ SYSHS 41_ STRDG 46_ RRDRY 51_ SSDTT 56_ PLLNG 61_ SSQDR 66_ MFETM 71_ AIEIE 76_ QLLAR 81_ LTGVN 86_ DKMAE 91_ YTNSA 96_ GVPSL 101_ NAALM 106_ HTLQR 111_ HRDIL 116_ QDYTH 121_ EFHKT 126_ KANFM 131_ AIRER 136_ ENLMG 141_ SVRKD 146_ IESYK 151_ SGSGV 156_ NNRRT 161_ ELFLK 166_ EHDHL 171_ RNSDR 176_ LIEET 181_ ISIAM 186_ ATKEN 191_ MTSQR 196_ GMLKS 201_ IHSKM 206_ NTLAN 211_ RFPAV 216_ NSLIQ 221_ RINLR 226_ KRRDS 231_ LILGG 236_ VIGIC 241_TILLL
1: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi