Brain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14)
1_MGIFP 6_ GIILI 11_ FLRVK 16_ FATAA 21_ VIVSG 26_ HQKST 31_ TVSHE 36_ MSGLN 41_ WKPFV 46_ YGGLA 51_ SIVAE 56_ FGTFP 61_ VDLTK 66_ TRLQV 71_ QGQSI 76_ DARFK 81_ EIKYR 86_ GMFHA 91_ LFRIC 96_ KEEGV 101_ LALYS 106_ GIAPA 111_ LLRQA 116_ SYGTI 121_ KIGIY 126_ QSLKR 131_ LFVER 136_ LEDET 141_ LLINM 146_ ICGVV 151_ SGVIS 156_ STIAN 161_ PTDVL 166_ KIRMQ 171_ AQGSL 176_ FQGSM 181_ IGSFI 186_ DIYQQ 191_ EGTRG 196_ LWRGV 201_ VPTAQ 206_ RAAIV 211_ VGVEL 216_ PVYDI 221_ TKKHL 226_ ILSGM 231_ MGDTI 236_ LTHFV 241_ SSFTC 246_ GLAGA 251_ LASNP 256_ VDVVR 261_ TRMMN 266_ QRAIV 271_ GHVDL 276_ YKGTV 281_ DGILK 286_ MWKHE 291_ GFFAL 296_ YKGFW 301_ PNWLR 306_ LGPWN 311_ IIFFI 316_TYEQL
1: Transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate and glutamate and tricarboxylates (PubMed:31356773). May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also can mediate a very low unidirectional transport of anions including sulfate, phosphate, (S)-malate, citrate, L-aspartate and L-glutamate (PubMed:31356773). Maintains oxidative balance (through uncoupling activities) and ATP production (by modifying mitochondrial membrane potential) (PubMed:20600837). Is able to transport protons across lipid membranes (PubMed:22524567, PubMed:26182433). Also exhibits transmembrane chloride transport activity to a lesser extent (PubMed:22524567, PubMed:26182433). May modify mitochondrial respiratory efficiency and mitochondrial oxidant production (By similarity)