Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2)
1_MVDRG 6_ PLLTS 11_ AIIFY 16_ LAIGA 21_ AIFEV 26_ LEEPH 31_ WKEAK 36_ KNYYT 41_ QKLHL 46_ LKEFP 51_ CLGQE 56_ GLDKI 61_ LEVVS 66_ DAAGQ 71_ GVAIT 76_ GNQTF 81_ NNWNW 86_ PNAMI 91_ FAATV 96_ ITTIG 101_ YGNVA 106_ PKTPA 111_ GRLFC 116_ VFYGL 121_ FGVPL 126_ CLTWI 131_ SALGK 136_ FFGGR 141_ AKRLG 146_ QFLTK 151_ RGVSL 156_ RKAQI 161_ TCTVI 166_ FIVWG 171_ VLVHL 176_ VIPPF 181_ VFMVT 186_ EGWNY 191_ IEGLY 196_ YSFIT 201_ ISTIG 206_ FGDFV 211_ AGVNP 216_ SANYH 221_ ALYRY 226_ FVELW 231_ IYLGL 236_ AWLSL 241_ FVNWK 246_ VSMFV 251_ EVHKA 256_ IKKRR 261_ RRRKE 266_ SFESS 271_ PHSRK 276_ ALQVK 281_ GSTAS 286_ KDVNI 291_ FSFLS 296_ KKEET 301_ YNDLI 306_ KQIGK 311_ KAMKT 316_ SGGGE 321_ TGPGP 326_ GLGPQ 331_ GGGLP 336_ ALPPS 341_ LVPLV 346_ VYSKN 351_ RVPTL 356_ EEVSQ 361_ TLRSK 366_ GHVSR 371_ SPDEE 376_ AVARA 381_ PEDSS 386_ PAPEV 391_ FMNQL 396_ DRISE 401_ ECEPW 406_ DAQDY 411_ HPLIF 416_ QDASI 421_ TFVNT 426_ EAGLS 431_ DEETS 436_ KSSLE 441_ DNLAG 446_ EESPQ 451_ QGAEA 456_ KAPLN 461_ MGEFP 466_ SSSES 471_ TFTST 476_ ESELS 481_ VPYEQ 486_ LMNEY 491_NKANS
1: K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate (PubMed:26919430, PubMed:36063992, PubMed:9812978). Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties (PubMed:36063992)