Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT)
1_MVQWK 6_ RLCQL 11_ HYLWA 16_ LGCYM 21_ LLATV 26_ ALKLS 31_ FRLKC 36_ DSDHL 41_ GLESR 46_ ESQSQ 51_ YCRNI 56_ LYNFL 61_ KLPAK 66_ RSINC 71_ SGVTR 76_ GDQEA 81_ VLQAI 86_ LNNLE 91_ VKKKR 96_ EPFTD 101_ THYLS 106_ LTRDC 111_ EHFKA 116_ ERKFI 121_ QFPLS 126_ KEEVE 131_ FPIAY 136_ SMVIH 141_ EKIEN 146_ FERLL 151_ RAVYA 156_ PQNIY 161_ CVHVD 166_ EKSPE 171_ TFKEA 176_ VKAII 181_ SCFPN 186_ VFIAS 191_ KLVRV 196_ VYASW 201_ SRVQA 206_ DLNCM 211_ EDLLQ 216_ SSVPW 221_ KYFLN 226_ TCGTD 231_ FPIKS 236_ NAEMV 241_ QALKM 246_ LNGRN 251_ SMESE 256_ VPPKH 261_ KETRW 266_ KYHFE 271_ VVRDT 276_ LHLTN 281_ KKKDP 286_ PPYNL 291_ TMFTG 296_ NAYIV 301_ ASRDF 306_ VQHVL 311_ KNPKS 316_ QQLIE 321_ WVKDT 326_ YSPDE 331_ HLWAT 336_ LQRAR 341_ WMPGS 346_ VPNHP 351_ KYDIS 356_ DMTSI 361_ ARLVK 366_ WQGHE 371_ GDIDK 376_ GAPYA 381_ PCSGI 386_ HQRAI 391_ CVYGA 396_ GDLNW 401_ MLQNH 406_ HLLAN 411_ KFDPK 416_ VDDNA 421_ LQCLE 426_ EYLRY 431_KAIYG
1: Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Also has I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development