Gene name: MED26

Uniprot entry:

O95402

Protein names:

Mediator of RNA polymerase II transcription subunit 26 (Activator-recruited cofactor 70 kDa component) (ARC70) (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26) (Transcriptional coactivator CRSP70)

Protein sequence:

1_MTAAP 6_ ASPQQ 11_ IRDRL 16_ LQAID 21_ PQSNI 26_ RNMVA 31_ VLEVI 36_ SSLEK 41_ YPITK 46_ EALEE 51_ TRLGK 56_ LINDV 61_ RKKTK 66_ NEELA 71_ KRAKK 76_ LLRSW 81_ QKLIE 86_ PAHQH 91_ EAALR 96_ GLAGA 101_ TGSAN 106_ GGAHN 111_ CRPEV 116_ GAAGP 121_ PRSIH 126_ DLKSR 131_ NDLQR 136_ LPGQR 141_ LDRLG 146_ SRKRR 151_ GDQRD 156_ LGHPG 161_ PPPKV 166_ SKASH 171_ DPLVP 176_ NSSPL 181_ PTNGI 186_ SGSPE 191_ SFASS 196_ LDGSG 201_ HAGPE 206_ GSRLE 211_ RDEND 216_ KHSGK 221_ IPVNA 226_ VRPHT 231_ SSPGL 236_ GKPPG 241_ PCLQP 246_ KASVL 251_ QQLDR 256_ VDETP 261_ GPPHP 266_ KGPPR 271_ CSFSP 276_ RNSRH 281_ EGSFA 286_ RQQSL 291_ YAPKG 296_ SVPSP 301_ SPRPQ 306_ ALDAT 311_ QVPSP 316_ LPLAQ 321_ PSTPP 326_ VRRLE 331_ LLPSA 336_ ESPVC 341_ WLEQP 346_ ESHQR 351_ LAGPG 356_ CKAGL 361_ SPAEP 366_ LLSRA 371_ GFSPD 376_ SSKAD 381_ SDAAS 386_ SGGSD 391_ SKKKK 396_ RYRPR 401_ DYTVN 406_ LDGQV 411_ AEAGV 416_ KPVRL 421_ KERKL 426_ TFDPM 431_ TRQIK 436_ PLTQK 441_ EPVRA 446_ DSPVH 451_ MEQQS 456_ RTELD 461_ KQEAK 466_ ASLQS 471_ PFEQT 476_ NWKEL 481_ SRNEI 486_ IQSYL 491_ SRQSS 496_ LLSSS 501_ GAQTP 506_ GAHHF 511_ MSEYL 516_ KQEES 521_ TRQGA 526_ RQLHV 531_ LVPQS 536_ PPTDL 541_ PGLTR 546_ EVTQD 551_ DLDRI 556_ QASQW 561_ PGVNG 566_ CQDTQ 571_ GNWYD 576_ WTQCI 581_ SLDPH 586_ GDDGR 591_LNILP

Protein annotations

Protein functions:

1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors