BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
1_MSALR 6_ RSGYG 11_ PSDGP 16_ SYGRY 21_ YGPGG 26_ GDVPV 31_ HPPPP 36_ LYPLR 41_ PEPPQ 46_ PPISW 51_ RVRGG 56_ GPAET 61_ TWLGE 66_ GGGGD 71_ GYYPS 76_ GGAWP 81_ EPGRA 86_ GGSHQ 91_ EQPPY 96_ PSYNS 101_ NYWNS 106_ TARSR 111_ APYPS 116_ TYPVR 121_ PELQG 126_ QSLNS 131_ YTNGA 136_ YGPTY 141_ PPGPG 146_ ANTAS 151_ YSGAY 156_ YAPGY 161_ TQTSY 166_ STEVP 171_ STYRS 176_ SGNSP 181_ TPVSR 186_ WIYPQ 191_ QDCQT 196_ EAPPL 201_ RGQVP 206_ GYPPS 211_ QNPGM 216_ TLPHY 221_ PYGDG 226_ NRSVP 231_ QSGPT 236_ VRPQE 241_ DAWAS 246_ PGAYG 251_ MGGRY 256_ PWPSS 261_ APSAP 266_ PGNLY 271_ MTEST 276_ SPWPS 281_ SGSPQ 286_ SPPSP 291_ PVQQP 296_ KDSSY 301_ PYSQS 306_ DQSMN 311_ RHNFP 316_ CSVHQ 321_ YESSG 326_ TVNND 331_ DSDLL 336_ DSQVQ 341_ YSAEP 346_ QLYGN 351_ ATSDH 356_ PNNQD 361_ QSSSL 366_ PEECV 371_ PSDES 376_ TPPSI 381_ KKIIH 386_ VLEKV 391_ QYLEQ 396_ EVEEF 401_ VGKKT 406_ DKAYW 411_ LLEEM 416_ LTKEL 421_ LELDS 426_ VETGG 431_ QDSVR 436_ QARKE 441_ AVCKI 446_ QAILE 451_KLEKK
1: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria