Protein transport protein Sec24A (SEC24-related protein A)
1_MSQPG 6_ IPASG 11_ GAPAS 16_ LQAQN 21_ GAALA 26_ SGSPY 31_ TNGPV 36_ QNALL 41_ SSQES 46_ VSQGY 51_ NFQLP 56_ GSYPH 61_ PIPAK 66_ TLNPV 71_ SGQSN 76_ YGGSQ 81_ GSGQT 86_ LNRPP 91_ VASNP 96_ VTPSL 101_ HSGPA 106_ PRMPL 111_ PASQN 116_ PATTP 121_ MPSSS 126_ FLPEA 131_ NLPPP 136_ LNWQY 141_ NYPST 146_ ASQTN 151_ HCPRA 156_ SSQPT 161_ VSGNT 166_ SLTTN 171_ HQYVS 176_ SGYPS 181_ LQNSF 186_ IKSGP 191_ SVPPL 196_ VNPPL 201_ PTTFQ 206_ PGAPH 211_ GPPPA 216_ GGPPP 221_ VRALT 226_ PLTSS 231_ YRDVP 236_ QPLFN 241_ SAVNQ 246_ EGITS 251_ NTNNG 256_ SMVVH 261_ SSYDE 266_ IEGGG 271_ LLATP 276_ QLTNK 281_ NPKMS 286_ RSVGY 291_ SYPSL 296_ PPGYQ 301_ NTTPP 306_ GATGV 311_ PPSSL 316_ NYPSG 321_ PQAFT 326_ QTPLG 331_ ANHLT 336_ TSMSG 341_ LSLQP 346_ EGLRV 351_ VNLLQ 356_ ERNML 361_ PSTPL 366_ KPPVP 371_ NLHED 376_ IQKLN 381_ CNPEL 386_ FRCTL 391_ TSIPQ 396_ TQALL 401_ NKAKL 406_ PLGLL 411_ LHPFK 416_ DLVQL 421_ PVVTS 426_ STIVR 431_ CRSCR 436_ TYINP 441_ FVSFL 446_ DQRRW 451_ KCNLC 456_ YRVND 461_ VPEEF 466_ LYNPL 471_ TRVYG 476_ EPHRR 481_ PEVQN 486_ ATIEF 491_ MAPSE 496_ YMLRP 501_ PQPPV 506_ YLFVF 511_ DVSHN 516_ AVETG 521_ YLNSV 526_ CQSLL 531_ DNLDL 536_ LPGNT 541_ RTKIG 546_ FITFD 551_ STIHF 556_ YGLQE 561_ SLSQP 566_ QMLIV 571_ SDIED 576_ VFIPM 581_ PENLL 586_ VNLNE 591_ SKELV 596_ QDLLK 601_ TLPQM 606_ FTKTL 611_ ETQSA 616_ LGPAL 621_ QAAFK 626_ LMSPT 631_ GGRMS 636_ VFQTQ 641_ LPTLG 646_ VGALK 651_ PREEP 656_ NHRSS 661_ AKDIH 666_ MTPST 671_ DFYKK 676_ LALDC 681_ SGQQV 686_ AVDLF 691_ LLSGQ 696_ YSDLA 701_ SLGCI 706_ SRYSA 711_ GSVYY 716_ YPSYH 721_ HQHNP 726_ VQVQK 731_ LQKEL 736_ QRYLT 741_ RKIGF 746_ EAVMR 751_ IRCTK 756_ GLSIH 761_ TFHGN 766_ FFVRS 771_ TDLLS 776_ LPNVN 781_ PDAGY 786_ AVQMS 791_ VEESL 796_ TDTQL 801_ VSFQS 806_ ALLYT 811_ SSKGE 816_ RRIRV 821_ HTLCL 826_ PVVST 831_ LNDVF 836_ LGADV 841_ QAISG 846_ LLANM 851_ AVDRS 856_ MTASL 861_ SDARD 866_ ALVNA 871_ VIDSL 876_ SAYRS 881_ SVLSN 886_ QQPGL 891_ MVPFS 896_ LRLFP 901_ LFVLA 906_ LLKQK 911_ SFQTG 916_ TNARL 921_ DERIF 926_ AMCQV 931_ KNQPL 936_ VYLML 941_ TTHPS 946_ LYRVD 951_ NLSDE 956_ GALNI 961_ SDRTI 966_ PQPPI 971_ LQLSV 976_ EKLSR 981_ DGAFL 986_ MDAGS 991_ VLMLW 996_ VGKNC 1001_ TQNFL 1006_ SQVLG 1011_ VQNYA 1016_ SIPQP 1021_ MTDLP 1026_ ELDTP 1031_ ESARI 1036_ IAFIS 1041_ WLREQ 1046_ RPFFP 1051_ ILYVI 1056_ RDESP 1061_ MKANF 1066_ LQNMI 1071_ EDRTE 1076_ SALSY 1081_ YEFLL 1086_HIQQQ
1: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:17499046, PubMed:18843296, PubMed:20427317). Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes (PubMed:17499046, PubMed:18843296)