Ras-related protein Rab-3D
1_MASAG 6_ DTQAG 11_ PRDAA 16_ DQNFD 21_ YMFKL 26_ LLIGN 31_ SSVGK 36_ TSFLF 41_ RYADD 46_ SFTPA 51_ FVSTV 56_ GIDFK 61_ VKTVY 66_ RHDKR 71_ IKLQI 76_ WDTAG 81_ QERYR 86_ TITTA 91_ YYRGA 96_ MGFLL 101_ MYDIA 106_ NQESF 111_ AAVQD 116_ WATQI 121_ KTYSW 126_ DNAQV 131_ ILVGN 136_ KCDLE 141_ DERVV 146_ PAEDG 151_ RRLAD 156_ DLGFE 161_ FFEAS 166_ AKENI 171_ NVKQV 176_ FERLV 181_ DVICE 186_ KMNES 191_ LEPSS 196_ SSGSN 201_ GKGPA 206_ VGDAP 211_APQPS
1: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes (By similarity)