Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)
1_MSAYP 6_ KSYNP 11_ FDDDG 16_ EDEGA 21_ RPAPW 26_ RDARD 31_ LPDGP 36_ DAPAD 41_ RQQYL 46_ RQEVL 51_ RRAEA 56_ TAAST 61_ SRSLA 66_ LMYES 71_ EKVGV 76_ ASSEE 81_ LARQR 86_ GVLER 91_ TEKMV 96_ DKMDQ 101_ DLKIS 106_ QKHIN 111_ SIKSV 116_ FGGLV 121_ NYFKS 126_ KPVET 131_ PPEQN 136_ GTLTS 141_ QPNNR 146_ LKEAI 151_ STSKE 156_ QEAKY 161_ QASHP 166_ NLRKL 171_ DDTDP 176_ VPRGA 181_ GSAMS 186_ TDAYP 191_ KNPHL 196_ RAYHQ 201_ KIDSN 206_ LDELS 211_ MGLGR 216_ LKDIA 221_ LGMQT 226_ EIEEQ 231_ DDILD 236_ RLTTK 241_ VDKLD 246_ VNIKS 251_TERKV
1: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions