Gene name: FGF19

Uniprot entry:

O95750

Protein names:

Fibroblast growth factor 19 (FGF-19)

Protein sequence:

1_MRSGC 6_ VVVHV 11_ WILAG 16_ LWLAV 21_ AGRPL 26_ AFSDA 31_ GPHVH 36_ YGWGD 41_ PIRLR 46_ HLYTS 51_ GPHGL 56_ SSCFL 61_ RIRAD 66_ GVVDC 71_ ARGQS 76_ AHSLL 81_ EIKAV 86_ ALRTV 91_ AIKGV 96_ HSVRY 101_ LCMGA 106_ DGKMQ 111_ GLLQY 116_ SEEDC 121_ AFEEE 126_ IRPDG 131_ YNVYR 136_ SEKHR 141_ LPVSL 146_ SSAKQ 151_ RQLYK 156_ NRGFL 161_ PLSHF 166_ LPMLP 171_ MVPEE 176_ PEDLR 181_ GHLES 186_ DMFSS 191_ PLETD 196_ SMDPF 201_ GLVTG 206_ LEAVR 211_SPSFE

Protein annotations

Protein functions:

1: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4