Ras-related protein Rab-36
1_MVIAG 6_ ASWML 11_ GRAAA 16_ SPTQT 21_ PPTTS 26_ TIRVA 31_ RRSRV 36_ ALVAM 41_ VIAAA 46_ GSGGP 51_ GRAEP 56_ QLSQP 61_ SLDCG 66_ RMRSS 71_ LTPLG 76_ PPVSR 81_ DRVIA 86_ SFPKW 91_ YTPEA 96_ CLQLR 101_ EHFHG 106_ QVSAA 111_ CQRRN 116_ TGTVG 121_ LKLSK 126_ VVVVG 131_ DLYVG 136_ KTSLI 141_ HRFCK 146_ NVFDR 151_ DYKAT 156_ IGVDF 161_ EIERF 166_ EIAGI 171_ PYSLQ 176_ IWDTA 181_ GQEKF 186_ KCIAS 191_ AYYRG 196_ AQVII 201_ TAFDL 206_ TDVQT 211_ LEHTR 216_ QWLED 221_ ALREN 226_ EAGSC 231_ FIFLV 236_ GTKKD 241_ LLSGA 246_ ACEQA 251_ EADAV 256_ HLARE 261_ MQAEY 266_ WSVSA 271_ KTGEN 276_ VKAFF 281_ SRVAA 286_ LAFEQ 291_ SVLQD 296_ LERQS 301_ SARLQ 306_ VGNGD 311_ LIQME 316_ GSPPE 321_ TQESK 326_RPSSL
1: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion