U6 snRNA-associated Sm-like protein LSm8
1_MTSAL 6_ ENYIN 11_ RTVAV 16_ ITSDG 21_ RMIVG 26_ TLKGF 31_ DQTIN 36_ LILDE 41_ SHERV 46_ FSSSQ 51_ GVEQV 56_ VLGLY 61_ IVRGD 66_ NVAVI 71_ GEIDE 76_ ETDSA 81_ LDLGN 86_ IRAEP 91_LNSVA
1: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320)