Probable G-protein coupled receptor 75
1_MNSTG 6_ HLQDA 11_ PNATS 16_ LHVPH 21_ SQEGN 26_ STSLQ 31_ EGLQD 36_ LIHTA 41_ TLVTC 46_ TFLLA 51_ VIFCL 56_ GSYGN 61_ FIVFL 66_ SFFDP 71_ AFRKF 76_ RTNFD 81_ FMILN 86_ LSFCD 91_ LFICG 96_ VTAPM 101_ FTFVL 106_ FFSSA 111_ SSIPD 116_ AFCFT 121_ FHLTS 126_ SGFII 131_ MSLKT 136_ VAVIA 141_ LHRLR 146_ MVLGK 151_ QPNRT 156_ ASFPC 161_ TVLLT 166_ LLLWA 171_ TSFTL 176_ ATLAT 181_ LKTSK 186_ SHLCL 191_ PMSSL 196_ IAGKG 201_ KAILS 206_ LYVVD 211_ FTFCV 216_ AVVSV 221_ SYIMI 226_ AQTLR 231_ KNAQV 236_ RKCPP 241_ VITVD 246_ ASRPQ 251_ PFMGV 256_ PVQGG 261_ GDPIQ 266_ CAMPA 271_ LYRNQ 276_ NYNKL 281_ QHVQT 286_ RGYTK 291_ SPNQL 296_ VTPAA 301_ SRLQL 306_ VSAIN 311_ LSTAK 316_ DSKAV 321_ VTCVI 326_ IVLSV 331_ LVCCL 336_ PLGIS 341_ LVQVV 346_ LSSNG 351_ SFILY 356_ QFELF 361_ GFTLI 366_ FFKSG 371_ LNPFI 376_ YSRNS 381_ AGLRR 386_ KVLWC 391_ LQYIG 396_ LGFFC 401_ CKQKT 406_ RLRAM 411_ GKGNL 416_ EVNRN 421_ KSSHH 426_ ETNSA 431_ YMLSP 436_ KPQKK 441_ FVDQA 446_ CGPSH 451_ SKESM 456_ VSPKI 461_ SAGHQ 466_ HCGQS 471_ SSTPI 476_ NTRIE 481_ PYYSI 486_ YNSSP 491_ SQEES 496_ SPCNL 501_ QPVNS 506_ FGFAN 511_ SYIAM 516_ HYHTT 521_ NDLVQ 526_ EYDST 531_SAKQI
1: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor