Caveolae-associated protein 2 (Cavin-2) (PS-p68) (Phosphatidylserine-binding protein) (Serum deprivation-response protein)
1_MGEDA 6_ AQAEK 11_ FQHPG 16_ SDMRQ 21_ EKPSS 26_ PSPMP 31_ SSTPS 36_ PSLNL 41_ GNTEE 46_ AIRDN 51_ SQVNA 56_ VTVLT 61_ LLDKL 66_ VNMLD 71_ AVQEN 76_ QHKME 81_ QRQIS 86_ LEGSV 91_ KGIQN 96_ DLTKL 101_ SKYQA 106_ STSNT 111_ VSKLL 116_ EKSRK 121_ VSAHT 126_ RAVKE 131_ RMDRQ 136_ CAQVK 141_ RLENN 146_ HAQLL 151_ RRNHF 156_ KVLIF 161_ QEENE 166_ IPASV 171_ FVKQP 176_ VSGAV 181_ EGKEE 186_ LPDEN 191_ KSLEE 196_ TLHTV 201_ DLSSD 206_ DDLPH 211_ DEEAL 216_ EDSAE 221_ EKVEE 226_ SRAEK 231_ IKRSS 236_ LKKVD 241_ SLKKA 246_ FSRQN 251_ IEKKM 256_ NKLGT 261_ KIVSV 266_ ERREK 271_ IKKSL 276_ TSNHQ 281_ KISSG 286_ KSSPF 291_ KVSPL 296_ TFGRK 301_ KVREG 306_ ESHAE 311_ NETKS 316_ EDLPS 321_ SEQMP 326_ NDQEE 331_ ESFAE 336_ GHSEA 341_ SLASA 346_ LVEGE 351_ IAEEA 356_ AEKAT 361_ SRGSN 366_ SGMDS 371_ NIDLT 376_ IVEDE 381_ EEESV 386_ ALEQA 391_ QKVRY 396_ EGSYA 401_ LTSEE 406_ AERSD 411_ GDPVQ 416_PAVLQ
1: Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae (PubMed:19525939). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae (By similarity)