Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C)
1_MGNGK 6_ SIAGD 11_ QKAVP 16_ TQETH 21_ VWYRT 26_ FMMEY 31_ PSGLQ 36_ TLHEF 41_ KTLLG 46_ LQGLN 51_ QKANK 56_ HIDQV 61_ YNTFD 66_ TNKDG 71_ FVDFL 76_ EFIAA 81_ VNLIM 86_ QEKME 91_ QKLKW 96_ YFKLY 101_ DADGN 106_ GSIDK 111_ NELLD 116_ MFMAV 121_ QALNG 126_ QQTLS 131_ PEEFI 136_ NLVFH 141_ KIDIN 146_ NDGEL 151_ TLEEF 156_ INGMA 161_ KDQDL 166_ LEIVY 171_ KSFDF 176_ SNVLR 181_ VICNG 186_ KQPDM 191_ ETDSS 196_ KSPDK 201_AGLGK
1: Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure