Gene name: NUDT14

Uniprot entry:

O95848

Protein names:

Uridine diphosphate glucose pyrophosphatase NUDT14 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14)

Protein sequence:

1_MERIE 6_ GASVG 11_ RCAAS 16_ PYLRP 21_ LTLHY 26_ RQNGA 31_ QKSWD 36_ FMKTH 41_ DSVTV 46_ LLFNS 51_ SRRSL 56_ VLVKQ 61_ FRPAV 66_ YAGEV 71_ ERRFP 76_ GSLAA 81_ VDQDG 86_ PRELQ 91_ PALPG 96_ SAGVT 101_ VELCA 106_ GLVDQ 111_ PGLSL 116_ EEVAC 121_ KEAWE 126_ ECGYH 131_ LAPSD 136_ LRRVA 141_ TYWSG 146_ VGLTG 151_ SRQTM 156_ FYTEV 161_ TDAQR 166_ SGPGG 171_ GLVEE 176_ GELIE 181_ VVHLP 186_ LEGAQ 191_ AFADD 196_ PDIPK 201_ TLGVI 206_ FGVSW 211_ FLSQV 216_APNLD

Protein annotations

Protein functions:

1: Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose