Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (LCHC1) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)]
1_MSQLV 6_ ECVPN 11_ FSEGK 16_ NQEVI 21_ DAISG 26_ AITQT 31_ PGCVL 36_ LDVDA 41_ GPSTN 46_ RTVYT 51_ FVGPP 56_ ECVVE 61_ GALNA 66_ ARVAS 71_ RLIDM 76_ SRHQG 81_ EHPRM 86_ GALDV 91_ CPFIP 96_ VRGVS 101_ VDECV 106_ LCAQA 111_ FGQRL 116_ AEELD 121_ VPVYL 126_ YGEAA 131_ RMDSR 136_ RTLPA 141_ IRAGE 146_ YEALP 151_ KKLQQ 156_ ADWAP 161_ DFGPS 166_ SFVPS 171_ WGATA 176_ TGARK 181_ FLIAF 186_ NINLL 191_ GTKEQ 196_ AHRIA 201_ LNLRE 206_ QGRGK 211_ DQPGR 216_ LKKVQ 221_ GIGWY 226_ LDEKN 231_ LAQVS 236_ TNLLD 241_ FEVTA 246_ LHTVY 251_ EETCR 256_ EAQEL 261_ SLPVV 266_ GSQLV 271_ GLVPL 276_ KALLD 281_ AAAFY 286_ CEKEN 291_ LFILE 296_ EEQRI 301_ RLVVS 306_ RLGLD 311_ SLCPF 316_ SPKER 321_ IIEYL 326_ VPERG 331_ PERGL 336_ GSKSL 341_ RAFVG 346_ EVGAR 351_ SAAPG 356_ GGSVA 361_ AAAAA 366_ MGAAL 371_ GSMVG 376_ LMTYG 381_ RRQFQ 386_ SLDTT 391_ MRRLI 396_ PPFRE 401_ ASAKL 406_ TTLVD 411_ ADAEA 416_ FTAYL 421_ EAMRL 426_ PKNTP 431_ EEKDR 436_ RTAAL 441_ QEGLR 446_ RAVSV 451_ PLTLA 456_ ETVAS 461_ LWPAL 466_ QELAR 471_ CGNLA 476_ CRSDL 481_ QVAAK 486_ ALEMG 491_ VFGAY 496_ FNVLI 501_ NLRDI 506_ TDEAF 511_ KDQIH 516_ HRVSS 521_ LLQEA 526_ KTQAA 531_ LVLDC 536_LETRQ
1: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool
2: Binds and promotes bundling of vimentin filaments originating from the Golgi