Leucine-rich glioma-inactivated protein 1 (Epitempin-1)
1_MESER 6_ SKRMG 11_ NACIP 16_ LKRIA 21_ YFLCL 26_ LSALL 31_ LTEGK 36_ KPAKP 41_ KCPAV 46_ CTCTK 51_ DNALC 56_ ENARS 61_ IPRTV 66_ PPDVI 71_ SLSFV 76_ RSGFT 81_ EISEG 86_ SFLFT 91_ PSLQL 96_ LLFTS 101_ NSFDV 106_ ISDDA 111_ FIGLP 116_ HLEYL 121_ FIENN 126_ NIKSI 131_ SRHTF 136_ RGLKS 141_ LIHLS 146_ LANNN 151_ LQTLP 156_ KDIFK 161_ GLDSL 166_ TNVDL 171_ RGNSF 176_ NCDCK 181_ LKWLV 186_ EWLGH 191_ TNATV 196_ EDIYC 201_ EGPPE 206_ YKKRK 211_ INSLS 216_ SKDFD 221_ CIITE 226_ FAKSQ 231_ DLPYQ 236_ SLSID 241_ TFSYL 246_ NDEYV 251_ VIAQP 256_ FTGKC 261_ IFLEW 266_ DHVEK 271_ TFRNY 276_ DNITG 281_ TSTVV 286_ CKPIV 291_ IETQL 296_ YVIVA 301_ QLFGG 306_ SHIYK 311_ RDSFA 316_ NKFIK 321_ IQDIE 326_ ILKIR 331_ KPNDI 336_ ETFKI 341_ ENNWY 346_ FVVAD 351_ SSKAG 356_ FTTIY 361_ KWNGN 366_ GFYSH 371_ QSLHA 376_ WYRDT 381_ DVEYL 386_ EIVRT 391_ PQTLR 396_ TPHLI 401_ LSSSS 406_ QRPVI 411_ YQWNK 416_ ATQLF 421_ TNQTD 426_ IPNME 431_ DVYAV 436_ KHFSV 441_ KGDVY 446_ ICLTR 451_ FIGDS 456_ KVMKW 461_ GGSSF 466_ QDIQR 471_ MPSRG 476_ SMVFQ 481_ PLQIN 486_ NYQYA 491_ ILGSD 496_ YSFTQ 501_ VYNWD 506_ AEKAK 511_ FVKFQ 516_ ELNVQ 521_ APRSF 526_ THVSI 531_ NKRNF 536_ LFASS 541_ FKGNT 546_ QIYKH 551_VIVDL
1: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival