Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]
1_MQIEL 6_ STCFF 11_ LCLLR 16_ FCFSA 21_ TRRYY 26_ LGAVE 31_ LSWDY 36_ MQSDL 41_ GELPV 46_ DARFP 51_ PRVPK 56_ SFPFN 61_ TSVVY 66_ KKTLF 71_ VEFTD 76_ HLFNI 81_ AKPRP 86_ PWMGL 91_ LGPTI 96_ QAEVY 101_ DTVVI 106_ TLKNM 111_ ASHPV 116_ SLHAV 121_ GVSYW 126_ KASEG 131_ AEYDD 136_ QTSQR 141_ EKEDD 146_ KVFPG 151_ GSHTY 156_ VWQVL 161_ KENGP 166_ MASDP 171_ LCLTY 176_ SYLSH 181_ VDLVK 186_ DLNSG 191_ LIGAL 196_ LVCRE 201_ GSLAK 206_ EKTQT 211_ LHKFI 216_ LLFAV 221_ FDEGK 226_ SWHSE 231_ TKNSL 236_ MQDRD 241_ AASAR 246_ AWPKM 251_ HTVNG 256_ YVNRS 261_ LPGLI 266_ GCHRK 271_ SVYWH 276_ VIGMG 281_ TTPEV 286_ HSIFL 291_ EGHTF 296_ LVRNH 301_ RQASL 306_ EISPI 311_ TFLTA 316_ QTLLM 321_ DLGQF 326_ LLFCH 331_ ISSHQ 336_ HDGME 341_ AYVKV 346_ DSCPE 351_ EPQLR 356_ MKNNE 361_ EAEDY 366_ DDDLT 371_ DSEMD 376_ VVRFD 381_ DDNSP 386_ SFIQI 391_ RSVAK 396_ KHPKT 401_ WVHYI 406_ AAEEE 411_ DWDYA 416_ PLVLA 421_ PDDRS 426_ YKSQY 431_ LNNGP 436_ QRIGR 441_ KYKKV 446_ RFMAY 451_ TDETF 456_ KTREA 461_ IQHES 466_ GILGP 471_ LLYGE 476_ VGDTL 481_ LIIFK 486_ NQASR 491_ PYNIY 496_ PHGIT 501_ DVRPL 506_ YSRRL 511_ PKGVK 516_ HLKDF 521_ PILPG 526_ EIFKY 531_ KWTVT 536_ VEDGP 541_ TKSDP 546_ RCLTR 551_ YYSSF 556_ VNMER 561_ DLASG 566_ LIGPL 571_ LICYK 576_ ESVDQ 581_ RGNQI 586_ MSDKR 591_ NVILF 596_ SVFDE 601_ NRSWY 606_ LTENI 611_ QRFLP 616_ NPAGV 621_ QLEDP 626_ EFQAS 631_ NIMHS 636_ INGYV 641_ FDSLQ 646_ LSVCL 651_ HEVAY 656_ WYILS 661_ IGAQT 666_ DFLSV 671_ FFSGY 676_ TFKHK 681_ MVYED 686_ TLTLF 691_ PFSGE 696_ TVFMS 701_ MENPG 706_ LWILG 711_ CHNSD 716_ FRNRG 721_ MTALL 726_ KVSSC 731_ DKNTG 736_ DYYED 741_ SYEDI 746_ SAYLL 751_ SKNNA 756_ IEPRS 761_ FSQNS 766_ RHPST 771_ RQKQF 776_ NATTI 781_ PENDI 786_ EKTDP 791_ WFAHR 796_ TPMPK 801_ IQNVS 806_ SSDLL 811_ MLLRQ 816_ SPTPH 821_ GLSLS 826_ DLQEA 831_ KYETF 836_ SDDPS 841_ PGAID 846_ SNNSL 851_ SEMTH 856_ FRPQL 861_ HHSGD 866_ MVFTP 871_ ESGLQ 876_ LRLNE 881_ KLGTT 886_ AATEL 891_ KKLDF 896_ KVSST 901_ SNNLI 906_ STIPS 911_ DNLAA 916_ GTDNT 921_ SSLGP 926_ PSMPV 931_ HYDSQ 936_ LDTTL 941_ FGKKS 946_ SPLTE 951_ SGGPL 956_ SLSEE 961_ NNDSK 966_ LLESG 971_ LMNSQ 976_ ESSWG 981_ KNVSS 986_ TESGR 991_ LFKGK 996_ RAHGP 1001_ ALLTK 1006_ DNALF 1011_ KVSIS 1016_ LLKTN 1021_ KTSNN 1026_ SATNR 1031_ KTHID 1036_ GPSLL 1041_ IENSP 1046_ SVWQN 1051_ ILESD 1056_ TEFKK 1061_ VTPLI 1066_ HDRML 1071_ MDKNA 1076_ TALRL 1081_ NHMSN 1086_ KTTSS 1091_ KNMEM 1096_ VQQKK 1101_ EGPIP 1106_ PDAQN 1111_ PDMSF 1116_ FKMLF 1121_ LPESA 1126_ RWIQR 1131_ THGKN 1136_ SLNSG 1141_ QGPSP 1146_ KQLVS 1151_ LGPEK 1156_ SVEGQ 1161_ NFLSE 1166_ KNKVV 1171_ VGKGE 1176_ FTKDV 1181_ GLKEM 1186_ VFPSS 1191_ RNLFL 1196_ TNLDN 1201_ LHENN 1206_ THNQE 1211_ KKIQE 1216_ EIEKK 1221_ ETLIQ 1226_ ENVVL 1231_ PQIHT 1236_ VTGTK 1241_ NFMKN 1246_ LFLLS 1251_ TRQNV 1256_ EGSYD 1261_ GAYAP 1266_ VLQDF 1271_ RSLND 1276_ STNRT 1281_ KKHTA 1286_ HFSKK 1291_ GEEEN 1296_ LEGLG 1301_ NQTKQ 1306_ IVEKY 1311_ ACTTR 1316_ ISPNT 1321_ SQQNF 1326_ VTQRS 1331_ KRALK 1336_ QFRLP 1341_ LEETE 1346_ LEKRI 1351_ IVDDT 1356_ STQWS 1361_ KNMKH 1366_ LTPST 1371_ LTQID 1376_ YNEKE 1381_ KGAIT 1386_ QSPLS 1391_ DCLTR 1396_ SHSIP 1401_ QANRS 1406_ PLPIA 1411_ KVSSF 1416_ PSIRP 1421_ IYLTR 1426_ VLFQD 1431_ NSSHL 1436_ PAASY 1441_ RKKDS 1446_ GVQES 1451_ SHFLQ 1456_ GAKKN 1461_ NLSLA 1466_ ILTLE 1471_ MTGDQ 1476_ REVGS 1481_ LGTSA 1486_ TNSVT 1491_ YKKVE 1496_ NTVLP 1501_ KPDLP 1506_ KTSGK 1511_ VELLP 1516_ KVHIY 1521_ QKDLF 1526_ PTETS 1531_ NGSPG 1536_ HLDLV 1541_ EGSLL 1546_ QGTEG 1551_ AIKWN 1556_ EANRP 1561_ GKVPF 1566_ LRVAT 1571_ ESSAK 1576_ TPSKL 1581_ LDPLA 1586_ WDNHY 1591_ GTQIP 1596_ KEEWK 1601_ SQEKS 1606_ PEKTA 1611_ FKKKD 1616_ TILSL 1621_ NACES 1626_ NHAIA 1631_ AINEG 1636_ QNKPE 1641_ IEVTW 1646_ AKQGR 1651_ TERLC 1656_ SQNPP 1661_ VLKRH 1666_ QREIT 1671_ RTTLQ 1676_ SDQEE 1681_ IDYDD 1686_ TISVE 1691_ MKKED 1696_ FDIYD 1701_ EDENQ 1706_ SPRSF 1711_ QKKTR 1716_ HYFIA 1721_ AVERL 1726_ WDYGM 1731_ SSSPH 1736_ VLRNR 1741_ AQSGS 1746_ VPQFK 1751_ KVVFQ 1756_ EFTDG 1761_ SFTQP 1766_ LYRGE 1771_ LNEHL 1776_ GLLGP 1781_ YIRAE 1786_ VEDNI 1791_ MVTFR 1796_ NQASR 1801_ PYSFY 1806_ SSLIS 1811_ YEEDQ 1816_ RQGAE 1821_ PRKNF 1826_ VKPNE 1831_ TKTYF 1836_ WKVQH 1841_ HMAPT 1846_ KDEFD 1851_ CKAWA 1856_ YFSDV 1861_ DLEKD 1866_ VHSGL 1871_ IGPLL 1876_ VCHTN 1881_ TLNPA 1886_ HGRQV 1891_ TVQEF 1896_ ALFFT 1901_ IFDET 1906_ KSWYF 1911_ TENME 1916_ RNCRA 1921_ PCNIQ 1926_ MEDPT 1931_ FKENY 1936_ RFHAI 1941_ NGYIM 1946_ DTLPG 1951_ LVMAQ 1956_ DQRIR 1961_ WYLLS 1966_ MGSNE 1971_ NIHSI 1976_ HFSGH 1981_ VFTVR 1986_ KKEEY 1991_ KMALY 1996_ NLYPG 2001_ VFETV 2006_ EMLPS 2011_ KAGIW 2016_ RVECL 2021_ IGEHL 2026_ HAGMS 2031_ TLFLV 2036_ YSNKC 2041_ QTPLG 2046_ MASGH 2051_ IRDFQ 2056_ ITASG 2061_ QYGQW 2066_ APKLA 2071_ RLHYS 2076_ GSINA 2081_ WSTKE 2086_ PFSWI 2091_ KVDLL 2096_ APMII 2101_ HGIKT 2106_ QGARQ 2111_ KFSSL 2116_ YISQF 2121_ IIMYS 2126_ LDGKK 2131_ WQTYR 2136_ GNSTG 2141_ TLMVF 2146_ FGNVD 2151_ SSGIK 2156_ HNIFN 2161_ PPIIA 2166_ RYIRL 2171_ HPTHY 2176_ SIRST 2181_ LRMEL 2186_ MGCDL 2191_ NSCSM 2196_ PLGME 2201_ SKAIS 2206_ DAQIT 2211_ ASSYF 2216_ TNMFA 2221_ TWSPS 2226_ KARLH 2231_ LQGRS 2236_ NAWRP 2241_ QVNNP 2246_ KEWLQ 2251_ VDFQK 2256_ TMKVT 2261_ GVTTQ 2266_ GVKSL 2271_ LTSMY 2276_ VKEFL 2281_ ISSSQ 2286_ DGHQW 2291_ TLFFQ 2296_ NGKVK 2301_ VFQGN 2306_ QDSFT 2311_ PVVNS 2316_ LDPPL 2321_ LTRYL 2326_ RIHPQ 2331_ SWVHQ 2336_ IALRM 2341_ EVLGC 2346_EAQDL
1: Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa