Gene name: HPRT1

Uniprot entry:

P00492

Protein names:

Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)

Protein sequence:

1_MATRS 6_ PGVVI 11_ SDDEP 16_ GYDLD 21_ LFCIP 26_ NHYAE 31_ DLERV 36_ FIPHG 41_ LIMDR 46_ TERLA 51_ RDVMK 56_ EMGGH 61_ HIVAL 66_ CVLKG 71_ GYKFF 76_ ADLLD 81_ YIKAL 86_ NRNSD 91_ RSIPM 96_ TVDFI 101_ RLKSY 106_ CNDQS 111_ TGDIK 116_ VIGGD 121_ DLSTL 126_ TGKNV 131_ LIVED 136_ IIDTG 141_ KTMQT 146_ LLSLV 151_ RQYNP 156_ KMVKV 161_ ASLLV 166_ KRTPR 171_ SVGYK 176_ PDFVG 181_ FEIPD 186_ KFVVG 191_ YALDY 196_ NEYFR 201_ DLNHV 206_ CVISE 211_TGKAK

Protein annotations

Protein functions:

1: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway