Gene name: HPR

Uniprot entry:

P00739

Protein names:

Haptoglobin-related protein

Protein sequence:

1_MSDLG 6_ AVISL 11_ LLWGR 16_ QLFAL 21_ YSGND 26_ VTDIS 31_ DDRFP 36_ KPPEI 41_ ANGYV 46_ EHLFR 51_ YQCKN 56_ YYRLR 61_ TEGDG 66_ VYTLN 71_ DKKQW 76_ INKAV 81_ GDKLP 86_ ECEAV 91_ CGKPK 96_ NPANP 101_ VQRIL 106_ GGHLD 111_ AKGSF 116_ PWQAK 121_ MVSHH 126_ NLTTG 131_ ATLIN 136_ EQWLL 141_ TTAKN 146_ LFLNH 151_ SENAT 156_ AKDIA 161_ PTLTL 166_ YVGKK 171_ QLVEI 176_ EKVVL 181_ HPNYH 186_ QVDIG 191_ LIKLK 196_ QKVLV 201_ NERVM 206_ PICLP 211_ SKNYA 216_ EVGRV 221_ GYVSG 226_ WGQSD 231_ NFKLT 236_ DHLKY 241_ VMLPV 246_ ADQYD 251_ CITHY 256_ EGSTC 261_ PKWKA 266_ PKSPV 271_ GVQPI 276_ LNEHT 281_ FCVGM 286_ SKYQE 291_ DTCYG 296_ DAGSA 301_ FAVHD 306_ LEEDT 311_ WYAAG 316_ ILSFD 321_ KSCAV 326_ AEYGV 331_ YVKVT 336_ SIQHW 341_VQKTI

Protein annotations

Protein functions:

1: Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron