Renin (EC 3.4.23.15) (Angiotensinogenase)
1_MDGWR 6_ RMPRW 11_ GLLLL 16_ LWGSC 21_ TFGLP 26_ TDTTT 31_ FKRIF 36_ LKRMP 41_ SIRES 46_ LKERG 51_ VDMAR 56_ LGPEW 61_ SQPMK 66_ RLTLG 71_ NTTSS 76_ VILTN 81_ YMDTQ 86_ YYGEI 91_ GIGTP 96_ PQTFK 101_ VVFDT 106_ GSSNV 111_ WVPSS 116_ KCSRL 121_ YTACV 126_ YHKLF 131_ DASDS 136_ SSYKH 141_ NGTEL 146_ TLRYS 151_ TGTVS 156_ GFLSQ 161_ DIITV 166_ GGITV 171_ TQMFG 176_ EVTEM 181_ PALPF 186_ MLAEF 191_ DGVVG 196_ MGFIE 201_ QAIGR 206_ VTPIF 211_ DNIIS 216_ QGVLK 221_ EDVFS 226_ FYYNR 231_ DSENS 236_ QSLGG 241_ QIVLG 246_ GSDPQ 251_ HYEGN 256_ FHYIN 261_ LIKTG 266_ VWQIQ 271_ MKGVS 276_ VGSST 281_ LLCED 286_ GCLAL 291_ VDTGA 296_ SYISG 301_ STSSI 306_ EKLME 311_ ALGAK 316_ KRLFD 321_ YVVKC 326_ NEGPT 331_ LPDIS 336_ FHLGG 341_ KEYTL 346_ TSADY 351_ VFQES 356_ YSSKK 361_ LCTLA 366_ IHAMD 371_ IPPPT 376_ GPTWA 381_ LGATF 386_ IRKFY 391_ TEFDR 396_ RNNRI 401_GFALA
1: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney