Gene name: ASS1

Uniprot entry:

P00966

Protein names:

Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase)

Protein sequence:

1_MSSKG 6_ SVVLA 11_ YSGGL 16_ DTSCI 21_ LVWLK 26_ EQGYD 31_ VIAYL 36_ ANIGQ 41_ KEDFE 46_ EARKK 51_ ALKLG 56_ AKKVF 61_ IEDVS 66_ REFVE 71_ EFIWP 76_ AIQSS 81_ ALYED 86_ RYLLG 91_ TSLAR 96_ PCIAR 101_ KQVEI 106_ AQREG 111_ AKYVS 116_ HGATG 121_ KGNDQ 126_ VRFEL 131_ SCYSL 136_ APQIK 141_ VIAPW 146_ RMPEF 151_ YNRFK 156_ GRNDL 161_ MEYAK 166_ QHGIP 171_ IPVTP 176_ KNPWS 181_ MDENL 186_ MHISY 191_ EAGIL 196_ ENPKN 201_ QAPPG 206_ LYTKT 211_ QDPAK 216_ APNTP 221_ DILEI 226_ EFKKG 231_ VPVKV 236_ TNVKD 241_ GTTHQ 246_ TSLEL 251_ FMYLN 256_ EVAGK 261_ HGVGR 266_ IDIVE 271_ NRFIG 276_ MKSRG 281_ IYETP 286_ AGTIL 291_ YHAHL 296_ DIEAF 301_ TMDRE 306_ VRKIK 311_ QGLGL 316_ KFAEL 321_ VYTGF 326_ WHSPE 331_ CEFVR 336_ HCIAK 341_ SQERV 346_ EGKVQ 351_ VSVLK 356_ GQVYI 361_ LGRES 366_ PLSLY 371_ NEELV 376_ SMNVQ 381_ GDYEP 386_ TDATG 391_ FININ 396_ SLRLK 401_ EYHRL 406_QSKVT

Protein annotations

Protein functions:

1: One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues