Gene name: SPINK1

Uniprot entry:

P00995

Protein names:

Serine protease inhibitor Kazal-type 1 (Pancreatic secretory trypsin inhibitor) (Tumor-associated trypsin inhibitor) (TATI)

Protein sequence:

1_MKVTG 6_ IFLLS 11_ ALALL 16_ SLSGN 21_ TGADS 26_ LGREA 31_ KCYNE 36_ LNGCT 41_ KIYDP 46_ VCGTD 51_ GNTYP 56_ NECVL 61_ CFENR 66_ KRQTS 71_ILIQK

Protein annotations

Protein functions:

1: Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity)

2: In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production