Antithrombin-III (ATIII) (Serpin C1)
1_MYSNV 6_ IGTVT 11_ SGKRK 16_ VYLLS 21_ LLLIG 26_ FWDCV 31_ TCHGS 36_ PVDIC 41_ TAKPR 46_ DIPMN 51_ PMCIY 56_ RSPEK 61_ KATED 66_ EGSEQ 71_ KIPEA 76_ TNRRV 81_ WELSK 86_ ANSRF 91_ ATTFY 96_ QHLAD 101_ SKNDN 106_ DNIFL 111_ SPLSI 116_ STAFA 121_ MTKLG 126_ ACNDT 131_ LQQLM 136_ EVFKF 141_ DTISE 146_ KTSDQ 151_ IHFFF 156_ AKLNC 161_ RLYRK 166_ ANKSS 171_ KLVSA 176_ NRLFG 181_ DKSLT 186_ FNETY 191_ QDISE 196_ LVYGA 201_ KLQPL 206_ DFKEN 211_ AEQSR 216_ AAINK 221_ WVSNK 226_ TEGRI 231_ TDVIP 236_ SEAIN 241_ ELTVL 246_ VLVNT 251_ IYFKG 256_ LWKSK 261_ FSPEN 266_ TRKEL 271_ FYKAD 276_ GESCS 281_ ASMMY 286_ QEGKF 291_ RYRRV 296_ AEGTQ 301_ VLELP 306_ FKGDD 311_ ITMVL 316_ ILPKP 321_ EKSLA 326_ KVEKE 331_ LTPEV 336_ LQEWL 341_ DELEE 346_ MMLVV 351_ HMPRF 356_ RIEDG 361_ FSLKE 366_ QLQDM 371_ GLVDL 376_ FSPEK 381_ SKLPG 386_ IVAEG 391_ RDDLY 396_ VSDAF 401_ HKAFL 406_ EVNEE 411_ GSEAA 416_ ASTAV 421_ VIAGR 426_ SLNPN 431_ RVTFK 436_ ANRPF 441_ LVFIR 446_ EVPLN 451_ TIIFM 456_GRVAN
1: Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade (PubMed:15140129, PubMed:15853774). AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa (PubMed:15140129). Its inhibitory activity is greatly enhanced in the presence of heparin