Gene name: SERPINA3

Uniprot entry:

P01011

Protein names:

Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less]

Protein sequence:

1_MERML 6_ PLLAL 11_ GLLAA 16_ GFCPA 21_ VLCHP 26_ NSPLD 31_ EENLT 36_ QENQD 41_ RGTHV 46_ DLGLA 51_ SANVD 56_ FAFSL 61_ YKQLV 66_ LKAPD 71_ KNVIF 76_ SPLSI 81_ STALA 86_ FLSLG 91_ AHNTT 96_ LTEIL 101_ KGLKF 106_ NLTET 111_ SEAEI 116_ HQSFQ 121_ HLLRT 126_ LNQSS 131_ DELQL 136_ SMGNA 141_ MFVKE 146_ QLSLL 151_ DRFTE 156_ DAKRL 161_ YGSEA 166_ FATDF 171_ QDSAA 176_ AKKLI 181_ NDYVK 186_ NGTRG 191_ KITDL 196_ IKDLD 201_ SQTMM 206_ VLVNY 211_ IFFKA 216_ KWEMP 221_ FDPQD 226_ THQSR 231_ FYLSK 236_ KKWVM 241_ VPMMS 246_ LHHLT 251_ IPYFR 256_ DEELS 261_ CTVVE 266_ LKYTG 271_ NASAL 276_ FILPD 281_ QDKME 286_ EVEAM 291_ LLPET 296_ LKRWR 301_ DSLEF 306_ REIGE 311_ LYLPK 316_ FSISR 321_ DYNLN 326_ DILLQ 331_ LGIEE 336_ AFTSK 341_ ADLSG 346_ ITGAR 351_ NLAVS 356_ QVVHK 361_ AVLDV 366_ FEEGT 371_ EASAA 376_ TAVKI 381_ TLLSA 386_ LVETR 391_ TIVRF 396_ NRPFL 401_ MIIVP 406_ TDTQN 411_ IFFMS 416_KVTNP

Protein annotations

Protein functions:

1: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2