Vasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into: Arg-vasopressin (Arginine-vasopressin); Neurophysin 2 (Neurophysin-II); Copeptin]
1_MPDTM 6_ LPACF 11_ LGLLA 16_ FSSAC 21_ YFQNC 26_ PRGGK 31_ RAMSD 36_ LELRQ 41_ CLPCG 46_ PGGKG 51_ RCFGP 56_ SICCA 61_ DELGC 66_ FVGTA 71_ EALRC 76_ QEENY 81_ LPSPC 86_ QSGQK 91_ ACGSG 96_ GRCAA 101_ FGVCC 106_ NDESC 111_ VTEPE 116_ CREGF 121_ HRRAR 126_ ASDRS 131_ NATQL 136_ DGPAG 141_ ALLLR 146_ LVQLA 151_ GAPEP 156_FEPAQ
1: Specifically binds vasopressin
2: Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2) (PubMed:18174156)