Gene name: POMC

Uniprot entry:

P01189

Protein names:

Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin]

Protein sequence:

1_MPRSC 6_ CSRSG 11_ ALLLA 16_ LLLQA 21_ SMEVR 26_ GWCLE 31_ SSQCQ 36_ DLTTE 41_ SNLLE 46_ CIRAC 51_ KPDLS 56_ AETPM 61_ FPGNG 66_ DEQPL 71_ TENPR 76_ KYVMG 81_ HFRWD 86_ RFGRR 91_ NSSSS 96_ GSSGA 101_ GQKRE 106_ DVSAG 111_ EDCGP 116_ LPEGG 121_ PEPRS 126_ DGAKP 131_ GPREG 136_ KRSYS 141_ MEHFR 146_ WGKPV 151_ GKKRR 156_ PVKVY 161_ PNGAE 166_ DESAE 171_ AFPLE 176_ FKREL 181_ TGQRL 186_ REGDG 191_ PDGPA 196_ DDGAG 201_ AQADL 206_ EHSLL 211_ VAAEK 216_ KDEGP 221_ YRMEH 226_ FRWGS 231_ PPKDK 236_ RYGGF 241_ MTSEK 246_ SQTPL 251_ VTLFK 256_ NAIIK 261_NAYKK

Protein annotations

Protein functions:

1: Stimulates the adrenal glands to release cortisol

2: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes

3: Increases the pigmentation of skin by increasing melanin production in melanocytes

4: Endogenous orexigenic opiate

5: Endogenous opiate